What Is Methaqualone?

Methaqualone (hypnone, hemina)

Methaqualone (hypnone, hemina)

English name:

Methaqualone (Hyminal, Melsedin)

Traits:

This product is white crystalline powder, odorless, bitter taste; easily soluble in ethanol, almost insoluble in water.

Function and mechanism:

It mainly acts on the cerebral cortex and has sedative and hypnotic effects. The hypnotic effect is strong and onset quickly, its hypnotic effect intensity is 3-8 times that of phenobarbital and 3 times that of Grummit. It can improve sleep quality without discomfort after waking. Greater security.

Pharmacokinetics:

It is easily absorbed orally and exerts its effect 10-30 minutes after taking the medicine, which can be maintained for 6-8 hours. The half-life of this product is about 20-40h. It is excreted from the urine in combination with glucuronic acid after being metabolized by the liver.

Precautions:

Occasionally mild discomfort, such as dizziness, drowsiness, etc., a small number of patients may have a rash, numbness of the mouth, tongue, limbs, and transient mental disorders. Individual patients may have palpitations, nausea, vomiting, and general weakness. Patients with liver dysfunction should be used with caution, it should not be used in patients with mental illness, pregnant women should not use it. This amount of poisoning can cause respiratory depression. Long-term use of this product can produce tolerance and dependence. It should be noted that continuous use should generally not exceed 3 months.

Clinical application:

It is mainly used for insomnia, neurasthenia and pre-anesthetic administration.

Usage measurement:

Hypnosis: Oral, 100-200mg / time, taken before bedtime. Sedation: 100 mg / time, 3 times / d. Pediatric weight loss.

preparation:

Tablet: 100mg, 200mg.