What Is Oxymetazoline?

Oxymetazoline is an -receptor agonist, which has a good peripheral vasoconstriction effect. It directly stimulates vascular -1 receptors to cause vasoconstriction of the nasal mucosa, thereby reducing congestion and edema caused by inflammation. The effect is rapid, it can take effect in a few minutes, it can be maintained for several hours, and it can effectively relieve nasal congestion. This product can still inhibit the release of allergenic and inflammatory substances such as histamine, it has an antihistamine effect, can inhibit the growth of nasal and throat mucosa saprophytic bacteria, and has a strong antibacterial and anti-inflammatory effect.

Basic Information

Chinese name

Oxymetazoline

Foreign name

oxymetazoline

EINECS

216-079-1

CAS NO.

1491-59-4

Molecular formula

C16H24N2O

Oxymetazoline indications

For acute rhinitis, chronic simple rhinitis, chronic hypertrophic rhinitis, allergic rhinitis (allergic rhinitis), nasal polyps, aviation sinusitis, aviation otitis media, nose bleeding, nasal obstructive snoring and other nasal obstructive diseases .

Clinical application of oxymetazoline

Nasal spray, for adults and children over 6 years old, 1 to 3 sprays at a time, for children 3 to 5 years old, 1 spray at a time, once in the morning or before bedtime.

Oxymetazoline adverse reactions

1. Frequent use of spray or drops can cause rebound nasal congestion, and prolonged use can cause drug-induced rhinitis.

2. A few people have slight burning sensations, acupuncture sensations, dry nasal mucosa, headaches, dizziness, and increased heart rate.

3. Rare allergic reactions.

Precautions for oxymetazoline

Pediatrics and pregnant women under the age of 2 are disabled. Patients with coronary heart disease, hypertension, hyperthyroidism, and diabetes should be used with caution. Frequent spraying can cause rebound nasal congestion, and prolonged use can cause drug-induced rhinitis. Patients receiving monoamine oxidase inhibitor therapy are contraindicated. Those who are allergic to this product are prohibited. Atrophic rhinitis and dry rhinitis are contraindicated. If long-term medication is needed, it should be used intermittently after 7 days of continuous use and then stopped for a few days. Seek immediate medical attention if overdose or serious adverse reactions occur.

(Note: The above content is only for introduction, the drug use must be carried out by a regular hospital under the guidance of a doctor.)