What is teicoplanin?
Teicoplanine is a glycopeptide antibiotic used to treat serious infections caused by gram -positive bacteria. It is mainly used for the treatment of organisms to which antibiotics of the first line do not respond or in patients who cannot tolerate them. This drug has a spectrum of effect, which is similar to the spectrum of vancomycin, another injection glycopeptide drug. Teicoplanin may not be available in some countries.
bacteria are microorganisms that infect the body and multiply quickly. Despite their small structure, bacteria are complicated and diverse structures. Simply classified, bacteria can be divided into gram-positive and gram-negative organisms by the structure of the cell wall, including the amount of peptidoglycans in their cell walls. Different antibiotics work in different stages of bacterial growth to eradicate the body. It inhibits the synthesis of bacterial cell wall positive to gram-positive. Is active against a number of organisms, among is staphylococcus aureus including metIcilin-resistant organisms, listeria monocytogenes and Clostridium difficile . Meticillin-resistant Staphylococcus aureus (MRSA) is an organism that can be very difficult to treat because of its resistance to standard therapy. Clostridium difficile causes serious diarrhea.
Teicoplanines can be used to treat bone, skin, heart, respiratory tract, urinary tract and gastrointestinal tract. The dose of used theicoplanine depends on the site and organism involved in the infection. It is administered as a daily dose, intravenously or intramuscularly, and the treatment time depends on the infection. In some infections such as osteomyolitis or bone infection, treatment may be needed for three weeks or more.
Use Teicoplanine is usually limited by this hospital, at least initially, as they are used only in severe infections that do not respondThey are used as injection for first -line medicines and primarily. Sometimes it is also used to treat infections in patients who cannot use other antibiotics, such as those who have an allergy to penicillin and cephalosporin. The clinical reaction is usually observed within 48-72 hours.
As with any drugs, theicoplanin may have adverse effects on drugs, including hypersensitivity or allergy. The patient will usually be carefully monitored to determine and respond to any possible side effects that could occur. The attending physician also takes into account any accompanying disease or medication before the introduction of teicoplanin therapy, as interactions could occur. Patients who have kidney disease may need a lower dose.