What is the connection between lipitor and grapefruit?
Lipitor® and Grapefruit can create a dangerous combination that can lead to serious problems in some patients, including rabdomyolysis, liver problems, kidney failure and sometimes death. It is extremely important that people who use the Lipitor® brand atorvastatin to refrain from all grapefruit products, including juice and supplements, while taking the medicine. People who need to use the statin medicine to help reduce their blood cholesterol and do not want to give up grapefruit, can discuss other options with their doctors, because not all statin drugs respond to Grapefruit as Lipitor®.
When a person consumes grapefruit or grapefruit juice, specific enzymes in the liver work to metabolize food or drink. These enzymes are the same enzymes that process the Lipitor® medicine and decompose it, so there are not too many medicines in the patient's body. These enzymes are unable to effectively break down the Lipitor® and grapefruitzarium, so people who consumeThey take grapefruit, they can end up with a dangerously high drug level in their systems.
consuming grapefruit or grapefruit juice at a different time during the day than when the patient is taking medication, the Lipitor® and Grapefruit do not make safe. The liver works to process the drug throughout the day and it is important to refrain from inhibition of enzymes in the drug processing. Other juices and fruit do not interact with Lipitor® in this way.
The combination of Lipitor® and grapefruit can lead to serious consequences. Too much statin can lead to rabdomyolysis, a condition that decomposes muscle tissue and releases proteins into the body that the kidneys cannot process properly. This can lead to kidney failure and even death in severe cases. High drug levels can also lead to liver problems of some cases clustering liver failure.
chemicals in grapefruit that cause processing the same liver enzymes asLipitor® is called furanocoumarins. Scientists from the University of North Carolina-Chapel Hill in the United States have identified these chemicals in 2006. Society of juice can use this research in the future for the development of grapefruit juice without Furanocoumarin for patients using Lipitor®, one of the most prescribed drugs in the United States and many other areas.
ZOCOR®, Simvastatin and Mevacor® drugs, drug lovastatin, are other cholesterol -reducing drugs that are divided by the same enzymes as Lipitor®. Patients taking these medicines should also refrain from eating grapefruit. Crestor®, Rosuvastatin, is a viable alternative for many patients taking statin drugs and do not want to give up grapefruit.