What is the difference between glipizide and gliburide?

Glipizide and Glyburide oral drugs are prescribed to treat diabetes 2. These drugs are members of the pharmaceutical class of the second -generation sulphonyl, which treats diabetes by stimulating pancreatic beta cells to release insulin and help the body effectively use insulin. The advantages of glipizide and gliburide are comparable to treatment - but not healing - for high blood sugar. However, drugs vary in absorption, half -life and the initial dose in patients who were newly diagnosed with type 2 diabetes. Both drugs are available in oral tablets, but glipisides are also available in prolonged tablets.

The recommended initial dose of glipizide is 5 milligrams a day. The use of glipizide with food slows its absorption. Its half -life is two to seven hours before it is excluded from the body. The common side effects of glipizide include diarrhea, dizziness and rash. Serious side effects that require a notification of a lawtor involves a dark colored urine, light -colored stools and yellowforces the eyes.

Glyburide's recommended initial dose is 2.5-5.0 milligrams per day. Food does not affect the absorption of gloyburide. The half -life of this drug is seven to 10 hours. Nausea, rash and heartburn include common side effects. The serious potential side effects include fever, swelling of the face and unusual bleeding.

GLIPISID and GLYBURID have proved to be as effective as the drugs of sulphonylum's first generation chlorpropamide and tolbutamide. However, only glipiside has shown the ability to be more efficient than those medicines. Glipizide and Glyburide share potential contradictions with non -steroidal anti -inflammatory drugs (NSAIDs), hormonal contraceptives, beta blockers and alcohol.

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type 1 diabetes cannot be treated with glipizide and gliburide. Although diabetes 1. Typosed by the inability of the body synthesize insulin, type 2 diabetes stems from the body incorrectly using the insulin producedwell. Glipizide and Glyburide do not support the production of sufficient insulin to balance the deficiency caused by diabetes 1.

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