What is Zoledronate?
Zoledronate is known under various brands, including Zometa® and Reclast®, and treats or prevents bone loss associated with certain types of conditions such as bone cancer or osteoporosis. The drug belongs to a group of drugs called bisphosphonates that increase cells in bone cells, so that the bone is lost with less regularity. In particular, zoledronate was useful either to prevent bone damage or bone loss due to real bone tumors or chemotherapy. It has also been shown to be effective in preventing deterioration or stimulating new bone cells in people suffering from osteoporosis and can be used to treat Paget's bone disease.
Since there are different conditions for which zoledronate can be prescribed, dosing varies. All drug forms are supplied by intravenous infusion and the infusion time is short, usually lasting about 15 minutes. The most differ, how often infusion occurs. For osteoporosis, Reclast® is given once a year. People with paget's diseaseOU bones can only receive one dose of zoledronate, but people with cancer can get this medicine every three to four weeks, while cancer treatment or conditions remain active.
Like all medicines, zoledronate has serious warnings and side effects. It should not be used during pregnancy and can be contraindicated if people have kidney disease because the drug is cleaned by the kidneys. Those with aspirin sensitivity may develop wheezing or breathing problems if they are taking this medicine, and there is a possibility that there will be a dangerous allergic reaction.
The biggest problem for most patients with any bisphosphonate is the potential to develop a condition called osteonecrosis of the jaw (onj). Although rare, this can cause a large worse of the jaw, which may be complicated if people already have dental problems or need any form of dental surgery in the treatment of bisphosphonate. Before startingIt is important to obtain a clean health account from a dentist with zoledronate.
common side effects that are less severe include fatigue, headache, dizziness, stomach and back pain and stomach complaints such as nausea, vomiting and diarrhea. In some cases, when zoledronate is used in cancer patients, it worsens cancer. Some patients also have problems with a number of eye states such as swelling or increased pressure in the eyes. Many people do not experience serious side effects and can quickly clarify the drug from the body, so any felt side effects have a short time. However, most bisphosphonates have some real risks that are balanced by real benefits for people who use them.