What is orotic acid?

Orotic acid is a naturally occurring substance produced in the human body by the intestinal flora. The acid is also known as vitamin B13 or pyrimidinecarboxylic acid . In fact, it is not vitamin, but was originally classified as such after the 60 was added to the diet of laboratory animals. Its adding to their food stimulated the heart of the heart and showed other benefits of similar vitamin. The amount of orotic acid acts as a counter for vitamin B12 deficiency and has a gentle effect on the B12 in the body. Instead of vitamin B12, the abundance of orotic acid is used - not completely replacing, but by slowing damage caused by the lack of B12. It is also used in the world of competitive bodybuilding, as it is expected to increase the production of adenosine triposphate (ATP), which is the main source of body energy. Orotic acid acts as a precursor phosphoribosylpyrophosphate (PRPP), which in turn is used in pyrimidine biosynthesis. The larger the amount of the PRPP is presentNot in the body, the more ATP can be made.

Orotates or salts of this orotic acid are also used in commercial applications as mineral carriers for dietary supplements. One example is lithium orotate, a combination of lithium and orotic acid salt. This is often used to treat stress, attention disorder with hyperactivity (ADHD) and alcoholism.

is widely available for commercial purchases and naturopaths is often recommended as an alternative to lithium carbonad. However, there are studies, such as the study conducted by SMITH and sciences in 1979, which show that lithium orotate is cleaned far lesse effectively by the kidneys than other lithium supplements. This has led to some concerns that lithium orotate can cause more damage than good.

The chemical structure of orotic acid makes it heterocyclic compound . This is organic and contain at least one atom uMelt except one element other than carbon, such as nitrogen or oxygen. When assembling, they form the structure of the ring.

excess orotic acid leads to a state known as orotic aciduria . This condition may be hereditary or caused by excessive consumption. In adults, it causes an urea cycle to be interrupted. In children, this may cause inhibition of DNA and RNA synthesis leading to mental or physical damage.