What is the role of thyroxine in the body?
thyroxine is one of the main hormones secreted from thyroid follicular cells. In the body it affects thyroxine body metabolism and affects protein synthesis. This is also important for human growth and development because it regulates bone growth and helps in the maturation of neurons. This hormone also increases the effect of catecholamin, the sensitivity of the body to adrenaline. There are health problems associated with low and high levels of this hormone in the body.
Thyroxine is also known as T4, because the molecular structure consists of thyronin molecule with four iodine molecules. The synthesis occurs in the thyroid gland. The hormone is released into the blood through the thyroid follicular cells. Approximately 80 percent of all T4 are produced in follicular cells.
In the body, T4 is transported to blood cells. Only free or unbound hormones are transmitted to the cells and are considered active. Up to 99 percent of thyroxine is actually tied to proteins in the blood. The concentration of free T4 individuals in the blood is very important PŘi medical examination and diagnosis.
This particular hormone affects metabolism by regulating how much oxygen they use cells and by creating body heat. In the liver T4 directly affects cellular breathing, the process of transformation of glucose and oxygen to energy and carbon dioxide. The presence of thyroxine promotes the first step of metabolism that passes from glucose to pyruvate. In the stomach and intestines T4 promotes muscle contraction and secretion of digestive juice.
As children are age, T4 is responsible for regulating growth and development. Hormones coordinate bone growth with age and also the development of heart and skeletal muscles. In the skin, the T4 is responsible for hair growth. As children mature, the presence of hormone results in the production of breast milk and the ability to pregnancy. During the development years, the T4 is also responsible for the normal development of nerves and neurons.
catecholamine effect refers to the body's response to stress, evokes years or combat reactionEven in the body. This response is caused by the presence of adrenaline and noradrenaline in the body. The presence of thyroxine increases the sensitivity of the body to catecholamine compounds.
Excessive or insufficiently active thyroid can lead to problems with T4 levels in the body. Too much T4, due to hyperthyroidism, results in nervousness, weight loss and other potentially serious health problems. Uncomfortable thyroid can result in a number of other health conditions, including developmental problems and weight gain. Accessories can be used to increase thyroxine levels in the body. Excessive thyroid gland is sometimes destroyed or removed and hormonal therapy is used to provide the necessary hormones for proper body function.