What is a pancreatic polypeptide?

pancreatic polypeptide is part of the family of pancreatic hormones. It is usually accompanied by neuropeptide Y and yy peptide. Of these three, the first pancreatic polypeptide was discovered. It contains 36 amino acids and is located not only in the abdominal but also in the stomach and gastrointestinal tract. Activity

in the bile bladder, pancreatic and intestines is slowed by pancreatic polypeptide. In addition, it stimulates the large intestine. Metabolic functions are affected by the secretion of pancreatic polypeptide and can also reduce metabolic energy and reduce the level of fatty acids in the body. Research has shown that patients with anorexia usually have reduced pancreatic polypeptide levels in their systems. It has also been shown to be present in patients with rare cancer tumors called ppomas.

Pancreatic cancer patients usually have elevated levels of PP in their systems. In some cases, these increased levels are the first indication that a tumor is present. Pancreatic polypeptide alsoindicates when the bile stones block the pipes.

Pancreatic polypeptide was first discovered in 1972 by colleagues working in various laboratories. Ninety-three percent PP is located in the pancreas and is also known as F-cells. Water diarrhea, if accompanied by certain tumors of the body, can be caused by pancreatic polypeptide.

PP diagnostics is difficult, with an accuracy of 50 to 60 percent. The exception of low diagnostic speed is the case of kidney failure, which usually produces elevated levels of PP. In addition, older men with endocrine tumors often occur with elevated PP levels in their test results. Pancreatic tumors show elevated PP levels 20 to 67 percent of the time. Some medical experts believe that reconnaissance tests should be ordered whenever the patient represents an increased level of PP, while others approach waiting and vision if the tumor cannot be located.