What Is an Acute-Phase Protein?

APP, acute phase protein. Infection, burns, surgery, and trauma can quickly induce the body to produce non-specific responses based on defense, such as elevated body temperature, elevated blood sugar, enhanced catabolism, negative nitrogen balance, and plasma The concentration of certain proteins increased rapidly. This response is called the acute phase response, and the expressed protein is called the acute phase protein.

Acute phase protein

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Chinese name
Acute phase protein
Foreign name
acute phase protein
Short name
APP
Expressive response
Acute phase reaction
APP, acute phase protein. Infection, burns, surgery, and trauma can quickly induce the body to produce non-specific responses based on defense, such as elevated body temperature, elevated blood sugar, enhanced catabolism, negative nitrogen balance, and plasma The concentration of certain proteins increased rapidly. This response is called the acute phase response, and the expressed protein is called the acute phase protein.
The concentration of APP in normal plasma is low. Under the effect of various stressors, some APP can increase by more than 1000 times, such as C-reactive protein, serum amyloid A, etc .; some APP only increase several times, such as 1-anti-pancreatic Proteases, 1-acid glycoproteins, etc .; some APPs only increase by about 50%, such as ceruloplasmin and complement C3; etc. There are also a few APPs that decrease during the acute phase and are called negative APPs.

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