What is the correction of the base?
Base excision is a mechanism in a cell cycle that allows DNA repair when the bases are damaged. Damage creates a small lesion that can lead to problems in the future, and the body relies on repairing excision for basic excision to solve DNA errors before multiplication. If the lesion is greater, it requires repairing the excision of nucleotides; This occurs when the change in the DNA is large enough to pull the helix from the shape. DNA monitors some very specific formulas and the body can recognize a base that does not belong because it contains incorrect foundations or bases out of service. After excision, there is a small gap in the DNA, which must be filled with the action of the DNA of the league and DNA polymerase, two other enzymes.
enzymes involved may vary according to species. In all cases, the cell is able to recognize the problem with DNA and can send appropriate enzymes to make a repair. Basic repair of excision can be compared to the repair of the knitting knit, which notices the wrong stitch. Rather than throwing knitting and giving up, it can carefully removestitch and repair it to restore the project so that it can continue. As with knitting, there are several ways to fix the problem, depending on the type and type of error.
DNA can be damaged in several ways. Oxygenation and alkylation are two ordinary culprits. Organisms exposed to ionizing radiation can also develop damage in their DNA. Basic repair of excision allows the body to be repaired as needed, when recognizing the fact that normal wear and tear, tend to create small errors in DNA over time. When the cell cannot identify the replaced or incorrect base, the DNA can be replicated and can complicate an error as seen when cells become cancer due to mixing that runs away.
Scientists study the repair of excision in the laboratory to learn more about how and why it will happen and what happens when it goes wrong or the body fails IDENTitle the problem with the DNA source. This information may be important for the treatment of conditions using a genetic or DNA component. It may also be useful for the development of medical treatments that may include direct handling of DNA. Enzymes involved in repairing the basic excision of the basic excision can also be used to insert or replace DNA to remove harmful genes or reduce the patient's DNA to solve the health problem.