What Is the Stratum Lucidum?

The transparent layer (statum lucidum) is located in the superficial layer of the granular layer and consists of 2-3 layers of flat cells. Cell boundaries are unclear, and the nucleus and organelles have disappeared due to the role of lysosomes. After HE staining, this layer was strongly eosinophilic and had a high refractive index. The ultrastructure of the cells is similar to that of the stratum corneum. [1]

Transparent layer

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The transparent layer (statum lucidum) is located in the shallow layer of the granular layer and consists of 2-3 layers.
The transparent layer is transformed from the granular layer cells, and the cells are closely arranged, and their boundaries are unclear. The nucleus degradation gradually disappeared, the transparent keratin particles in the cytoplasm had been liquefied and transparent, highly refractive, and eosinophilic. H-E staining was light pink and homogeneous. This layer will be slightly thinner in the thin epidermis, which is most obvious on the palm and sole skin. Electron microscopy showed that there were more tension filaments in the cells, and they were arranged tightly and regularly.
Surface layering

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