What Is a False Signal?

This hypothesis believes that proteins are first synthesized on the free ribosomes of the cytoplasmic matrix. When the polypeptide chain extends to about 80 amino acids, the signal sequence at the N-terminus is combined with the signal recognition particle, which suspends the peptide chain extension and prevents damage to the N-terminus of the new peptide. Fold before maturity; until the signal recognition particle binds to the berber protein (SRP receptor) on the endoplasmic reticulum membrane and returns to reuse, the peptide chain begins to extend again; the signal peptide introduces the peptide chain into the endoplasmic reticulum membrane, and the endoplasmic reticulum surface The signal peptidase cleaves the signal peptide, and the peptide chain continues to extend to complete synthesis.