What Is a Granular Cell Tumor?

There are two types of granulosa cell tumors, one is clinically malignant and histologically benign; the other is clinically and histologically malignant. The more commonly accepted malignant standards are:

Basic Information

English name

granular cell tumor

Visiting department

Oncology

Common locations

Skin or subcutaneous tissue

Common symptoms

Tumor border is unclear, can grow large and ulcerated, often with local lymph nodes or extensive visceral metastases

Clinical manifestations of granulocytoma

This disease is rare and often occurs in the skin or subcutaneous tissue, and a few are also found in the bladder and throat. The tumor boundary is unclear, it can grow very large and ulcerated, and local lymph nodes or extensive visceral metastases often occur.

Differential diagnosis of granulocytoma

1. Squamous cell carcinoma, although there are occasional particles in the cancer cells, there are desmosomes under the electron microscope, and the particles have a negative reaction to PAS staining.

2. Granular cell basal cell carcinoma. Although the granules are also positive for PAS staining, the nucleus of the granular cells is biased to one side, and the basal-like cells around the tumor cell cluster are arranged in a fence.

Granuloma treatment

Combined with clinical and pathological changes, surgery and chemotherapy were used.