What Is a Liver Function Test?
Liver function test is a test that detects various indicators related to liver function metabolism through various biochemical test methods to reflect the basic status of liver function. Because liver functions are diverse, there are many liver function tests.
Liver function test
- Chinese name
- Liver function test
- Foreign name
- liver function test
- Scope of application
- Clinical medicine
- Features
- Liver function assessment
- Liver function test is a test that detects various indicators related to liver function metabolism through various biochemical test methods to reflect the basic status of liver function. Because liver functions are diverse, there are many liver function tests.
- Liver function test is an auxiliary method for diagnosing hepatobiliary system diseases. In order to make a correct diagnosis of the disease, a comprehensive comprehensive analysis must be performed in combination with the patient's medical history, physical examination and imaging examination. It should also be pointed out that there are many items for liver function tests, but not every test item needs to be done. Usually, the doctor will choose a group or several tests based on the patient's medical history and symptoms.
- Because liver functions are diverse, there are many liver function tests. Related to liver function
- Liver function test items usually include: liver protein metabolism, bilirubin and bile acid metabolism, enzymes, lipid metabolism, liver excretion and detoxification.
- Recently, relevant departments have added five new items for liver function tests, as follows:
- 1,
- The following are normal values of liver function tests:
- 1. Total serum protein TP60-80g / L; albumin A35-55g / L; globulin G20-30g / L.
- Gu Bing
- When it comes to liver function, people immediately think of transaminase, and some even think that transaminase is liver function. In fact, there are many types of liver function. There are more than 700 experiments that reflect liver function. New experiments are still being developed and established, mainly including four major categories.
- Tests reflecting liver cell injury: including serum enzymes and serum iron. Serum enzymes are commonly used for testing, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ACP), -glutamyltransferase Peptidase (-GT) and so on. It has been clinically shown that ALT and AST can sensitively indicate liver cell damage and the degree of damage in various enzyme tests. ALT is most sensitive in response to acute liver cell damage, and AST is more sensitive to reflect the degree of damage. During the recovery period of acute hepatitis, although ALT is normal and -GT continues to increase, suggesting chronic hepatitis. Chronic hepatitis GT does not decrease continuously, suggesting disease activity.
- Tests reflecting liver excretion function: Detecting the excretory and clearing ability of the liver to certain endogenous (bilirubin, bile acid, etc.) or exogenous (dye, drugs, etc.) high intakes, commonly used in clinical quantification of bilirubin If total bilirubin is greater than 17.1 md / L, it is a case of jaundice. If the bilirubin increases progressively with ALT decrease, it is called enzymatic bile separation, which indicates that the disease is aggravated and it may be converted into severe hepatitis.
- Tests that reflect liver reserve function: Plasma protein (ALb) and prothrombin time (PT) are routine tests that measure liver reserve function to reflect its reserve capacity. Decreased ALb indicates decreased protein synthesis ability, and prolonged PT indicates decreased synthesis ability of various coagulation factors.
- Tests reflecting liver interstitial changes: Serum protein electrophoresis has basically replaced the turbid response, and the increased degree of -globulin can assess the evolution and prognosis of chronic liver disease, suggesting that Kupffer cells are dysfunctional and cannot endogenous in blood circulation Or intestinal-derived antigenic substance. In addition, the serum levels of hyaluronic acid, lamin, type III procollagen peptide and type IV collagen can reflect changes in liver endothelial cells, fat storage cells and fibroblasts, and are closely related to liver fibrosis and cirrhosis.
- Regular liver function tests are necessary. Because the liver is the body's largest parenchymal organ, it carries various physiological functions. When various causes
- Liver function reflects the physiological function of the liver. The liver function test consists of detecting liver disease, liver damage, identifying the cause of liver disease, judging prognosis, and identifying the cause of jaundice. Several representative indicators are often selected to understand liver function, such as protein metabolism function test, bilirubin metabolism function test, liver dye excretion test, and various serum enzyme tests. Including bilirubin, albumin,
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- Analysis of liver function test results
- 1. cause
- There are many liver function test methods, which shows that some test methods are not specific. When analyzing liver function test results clinically, to evaluate whether liver function is normal, the following issues need to be considered: [2]
- The cost of liver function tests is around 100.
- Regular liver function tests are necessary. Because the liver is the body's largest parenchymal organ, it carries various physiological functions. When various causes
- Physical Examination Knowledge: When taking a physical examination, when you want to check liver function, do you know how to choose? Here's how to choose a liver function test:
- 1. When the clinical suspicion of hepatitis or the diagnosis of acute hepatitis requires further understanding of the extent of the disease, GPT can be detected (
- 1. Liver function is normal, HBV-DNA is normal and has no symptoms of hepatitis. This type of HBV-DNA is also known as a carrier of hepatitis B. In this case, a health certificate can be obtained for the size of the liver.
- 2. Hepatic function is abnormal and HBV-DNA is positive (indicating that HBV is in the high replication stage). In this case, patients with HBV-sized Sanyang are highly infectious and cannot obtain a health certificate. Active treatment is required Only when the liver function is normal and the HBV-DNA is stable can a health certificate be obtained.