What is the P38 journey?
The P38 path is a cellular signaling cascade that plays a role in gene expression, cell growth and immunity. Signaling allows cells to regulate various functions and processes in response to the environment and internal allusions, which coordinates the function of the body. This particular way is involved in responses to environmental stress and can be activated in response to the presence of cytokines and other proteins in the body. It is a target for research because it can play a role in response to the disease. In response to specific environmental pressures, the path of P38 can create a ripple because a number of signals move through the cell and produce one of the four known kinases. P38 Alpha is one of the most studied.
It is possible that the P38 path can play a role in the development of autoimmune disease, asthma and allergies. The path is involved in the maturation of T-cells and other components of the immune system. Cell death can be regulated by processes along the P38 track as well as cell growth as it can be active during key phases of division and replication process of cellsin the human body. Research that monitors the development of specific kinases provides critical information about how they work and where they can be found in the body.
studies on the P38 track identified it as a potential objective of the drug. Because it is involved in inflammatory reactions, it is possible that drugs can block one of the steps in the cascade to prevent inflammation or reduce its severity. This has particularly important consequences for patients with autoimmune diseases who experience chronic inflammation because their bodies attack themselves. Blocking can maintain patients more comfortable and prevent complications caused by chronic inflammation such as scarring and nerve damage.
Scientists interested in this particular signaling of cells usually work for academic institutions, government agencies and private companies. They look at the different P38 pathways and the possibilities of interrupting or redirecting with carefully targeted drugs. Drug therapies focused on this path may have potentially serious side effects for patients, which is another subject of concerns in the ongoing research measures to identify pharmaceutical compounds to combat inflammation and immune conditions.