What is the immune privilege?

The body has a natural response to foreign antigens that cause diseases and diseases. This answer is called an immune response and each part of the body has this reaction to some extent. Sometimes there are parts of the body that do not have an immune response to foreign antigens. A shortage such as this is called the immune privilege. There are specific parts of the body that are common places of privileges that include eyes, central nervous system and placenta and fetus.

Foreign antigens enter the body and are introduced into T cells that are made by the immune system. Normally t cells fight antigens and also remember the introduction of antigens. By recalling the exposure of the antigen, when these antigens try to attack the body again, the immune system jumps into action with minimal effects. Unfortunately, the immune privilege prevents this process. Each place of privileges reacts similarly, but in a different area.

Usually, the eyes have their own immune cells as well as other areas of the body. These cells can cause complete immuneVerify the whole body when the eye is exposed to antigens. When the eye is an immune privilege, t cells develop a lack of reaction to each other. T cells and self -mothers are tied together, causing separate antigens to become inactive. In the case of non -active themselves, the antigens of non -introduction of foreign antigens in the eye will not let the immune response as it should, which leaves the eye vulnerable.

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immune privilege in the central nervous system plays a major role in stopping inflammatory immune responses. The central nervous system is separated from the systemic immune system by a blood-chind barrier. Research suggests that the immune privilege often comes from the white matter of the central nervous system. Although research is undergoing, it is clear that foreign antigens to the lymph nodes do not cause any response to the immune system.

During pregnancy, the mother's immune system is usually able to protectt of her body before exposing a foreign antigen without affecting the fetus or placenta. In some cases, the placenta and fetus may be immune privileges. Some research has shown that a woman's immune system detects a fetus or placenta as foreign antigen and attacks. This instance can provide an explanation of abortions that occur without other medical causes.

If the body has an area of ​​immune privileges and the immune system cannot prevent this area, a wide range of diseases and diseases may occur. The tissue graft is the common cause of man to develop the area of ​​privileges that have not yet existed. In most cases, organ transplantation is either accepted or rejected by the body, but if the privilege occurs as a result of transplantation, the organ may be attacked and damaged by foreign antigens.

Although the privilege can be harmful to the body, it can also be beneficial. As the area of ​​immune privileges is cut off from the immune system, it can be useful for tissue graftsy and transplantation. The immune system does not have so much opportunity to reject or attack as a result.