What Is Collecting Duct Carcinoma?

Breast cancer is one of the most common malignant tumors in women, and breast ductal cancer is the most common pathological type of breast cancer, which can account for about 70% of all breast cancer patients. Breast ductal cancer progresses as soon as it metastases, and its prognosis becomes significantly worse. The median survival time is only 15-30 months.

Breast cancer is one of the most common malignant tumors in women, and breast ductal cancer is the most common pathological type of breast cancer, which can account for about 70% of all breast cancer patients. Breast ductal cancer progresses as soon as it metastases, and its prognosis becomes significantly worse. The median survival time is only 15-30 months.

Chinese name

Ductal carcinoma of the breast

Foreign name

Ductal carcinoma of breast

Causes of breast ductal cancer and common diseases:

The etiology and pathological mechanism of breast cancer have not been fully elucidated, but epidemiological investigations found that early menarche, late menopause, infertility and the age of first term delivery are related to the occurrence of breast cancer, indicating that the occurrence of breast cancer Closely related to female endocrine. And the first-degree relatives who have a history of breast cancer have three times the risk of breast cancer than the general population, indicating that genes are also important factors affecting breast cancer.

Differential diagnosis of breast ductal cancer :

Breast ductal carcinoma Ductal carcinoma is divided into two groups: micro-invasive ductal carcinoma and invasive ductal carcinoma. The criteria for invasive ductal carcinoma are: (1) Cell atypia, enlarged nuclei, dense staining, uneven distribution of chromatin, and increased nuclear plasma ratio. (2) The cell arrangement is extremely disordered, and the tumor cells form a variety of arrangements in the duct. (3) Cancer cells infiltrate the surrounding stroma, fibrous interstitial hyperplasia around the cancer cells, proliferated fibrous interstitial rupture occurs at the contact with the cancer cells, Actin immunohistochemical staining is negative around the cancer cell nest, or positive around the cancer cell nest appears Rupture, cannot circle around the nest of cancer cells. Criteria for microinvasive ductal carcinoma: meet the previous three criteria, and at the same time meet one or more small and clear microfocal infiltrating fibrous interstitials. Hyperplasia of the mammary glands include fibroadenoses, fibroadenomas, ductal papillomatosis, and endothelial hyperplasia.

Breast ductal cancer examination:

(1) CT examination:

CT scan shows nodular masses in the breast, medium or slightly higher density, irregular or lobular shape; uneven density in the mass, there may be necrotic low-density areas or cystic changes, and grit-like Calcification; burr visible at the edge of the mass. The lesions in the enhanced scan were significantly enhanced, showing fast-forward and fast-out performance, and dynamic enhanced fast-forward and fast-out performance was more obvious. Contrast-enhanced CT has the characteristics of fast-in and fast-out, which refers to the rapid intensification of arterial lesions, and the degree of intensification declines quickly after delayed scanning. Reinforcement appears as uniform strengthening or ring-shaped uneven strengthening. As the tumor grows further, skin thickening can occur, with an orange peel-like change. Some tumors expand to the periphery and can invade the posterior breast fat space and pectoralis major muscles, milk ducts, Cooper's ligaments, etc. Invading nipples are also a manifestation of advanced breast cancer. Breast cancer can be enlarged by metastasis of the axillary lymph nodes and internal mammary lymph nodes, and enhanced scans show circular enhancement.

(Two) color Doppler ultrasound:

The advantages of color Doppler ultrasound in the diagnosis of breast diseases: First, it is not radioactive and is more suitable for young women, especially during pregnancy and lactation. Second, it is of great value in identifying the nature of breast masses, especially in the diagnosis of benign diseases, and can be diagnosed and guided as early as possible in clinical treatment. Third, it can clearly show the small structures in the breast, including subcutaneous tissue, glands and bones, etc., which is of great significance for determining the location and scope of the lesion. Fourth, ultrasound can also be used to puncture small tumors with ambiguous properties. For patients with breast abscesses, ultrasound-guided drainage can be performed.

Breast ductal cancer treatment principles:

It is mainly based on surgery, combined with chemotherapy, radiotherapy, endocrine therapy, and molecular targeted therapy. For some early breast cancer, surgery is preferred. Surgery can choose modified radical surgery or breast-conserving surgery. According to the postoperative pathology, further treatment was decided. For some advanced breast cancer, chemotherapy can be chosen first, and surgery is performed after the tumor has shrunk. Individualized treatment should be implemented according to the condition of each patient.