What Is Germinoma?

Penile tumors are a common disease in China. The age of onset of penile cancer is more than 30 years old. The early manifestations are papular, wart or ulcer lesions of the foreskin or penis head, which gradually increase and generally have no pain. Longer-lasting penile cancer is typical of cauliflower, and most of the penis is damaged by cancer. Patients generally do not have difficulty urinating, the urine line is scattered due to tumor blockage, and there is local pain or dysuria when there is infection, and there is a foul odor. Repeated bleeding of the tumor can lead to weight loss, anemia and failure. Advanced inguinal lymph node metastasis makes the lymph nodes enlarged and hard, and even fixes or forms ulcers and is prone to bleeding. Extensive lymph node metastasis can cause lower extremity edema.

Penile tumor

Overview of penile tumors

Penile tumors are a common disease in China. The age of onset of penile cancer is more than 30 years old. The early manifestations are papular, wart or ulcer lesions of the foreskin or penis head, which gradually increase and generally no pain. Longer-lasting penile cancer is typical of cauliflower, and most of the penis is damaged by cancer. Patients generally do not have difficulty urinating, the urine line is scattered due to tumor blockage, and there is local pain or dysuria when there is infection, and there is a foul smell. Repeated bleeding of the tumor can lead to weight loss, anemia and failure. Advanced inguinal lymph node metastasis makes the lymph nodes enlarged and hard, and even fixes or forms ulcers and is prone to bleeding. Extensive lymph node metastasis can cause lower extremity edema.

Penile tumor squamous cell carcinoma

Overview of penile tumors

Squamous cell carcinoma of the penis is a malignant tumor that originates from the squamous epithelium of the penis. It is more common in men aged 40 to 70 years. The incidence is related to HPV. Foreskin circumcision can maintain local hygiene of the genitals, reduce foreskin containing HPV and other carcinogens, reduce the chance of HPV infection, and effectively prevent the occurrence of penile cancer.

Pathological changes in penile tumors

Squamous cell carcinoma of the penis usually occurs in the penis glans or foreskin near the coronary sulcus. The macroscopic view is a nipple type or flat type: the nipple type looks like condyloma acuminata or cauliflower-like appearance; the flat local mucosa surface is gray, thickened, cracks are visible on the surface, and ulcers can gradually appear. Under the microscope, squamous cell carcinomas with different degrees of differentiation are generally well differentiated with obvious keratosis.

Verrucous carcinoma is a highly differentiated squamous cell carcinoma that occurs in the vulva mucosa of men or women and is low-grade malignant. The tumor grows from the outside to the inside in the shape of a papilla, and only partially infiltrates in a tongue-like manner, and rarely metastasizes. It is named after the general and microscopic views are similar to genital warts and the appearance is wart-like.

Clinicopathology of penile tumors

Squamous cell carcinoma of the penis progresses slowly and can be locally metastasized. Unless there is ulcer formation or infection, it is generally painless and often accompanied by bleeding. Early tumors can metastasize to the groin and sacral lymph nodes, and unless they are advanced, they are widespread and rare. The five-year survival rate can reach 70%.