What Is Hepatitis B Serology?

There are generally five items for testing for hepatitis B, also known as the five indicators of hepatitis B (HBV-M), or "two and a half", known as hepatitis B virus serological indicators.

HBV serological indicators

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ordinary inspection

There are generally five items for testing for hepatitis B, also known as the five indicators of hepatitis B (HBV-M), or "two and a half".

"Two and a half" inspection results are indicated by plus and minus signs (ie, +,-). (+) Means positive; (-) means negative. The five checks are:

Surface antigen (abbreviation: HBsAg);

-Surface antibodies (abbreviation: anti-HBs);

E antigen (abbreviation: HBeAg);

E antibody (abbreviation: anti-Be);

Core antibody (abbreviation: anti-HBc). ^[1]

Below we introduce these inspection items one by one.

Surface antigen (HBsAg)

Surface antigens are often referred to as "Australia" in the past. "Australia" is "

Liver fibrosis is a necessary stage for the development of chronic hepatitis to cirrhosis. At this stage, the most important pathological change of the liver is that a large amount of extracellular matrix (collagen, non-collagen glycoprotein, proteoglycan) is formed and deposited in the liver. The early deposition only appeared in the hepatocyte mesenchyme, but in the later stage, the fibrous hyperplasia extended to the interstitial space of hepatic parenchyma, and gradually formed fibrous cords and fibrous spaces. In the final stage, fibrous spaces were connected to form fibrous envelopes, leading to typical pathological features of liver cirrhosis Pseudolobule formation, this is the cirrhosis phase. Some patients with chronic hepatitis want to know their own fibrosis and the degree of fibrosis. The clinician will give him four checklists of serum fibrosis for measurement. These four indicators include serum type III collagen (PCIII), serum type IV collagen (VI), laminin (LN), and hyaluronic acid (HA). After years of clinical validation, these four serological indicators can basically reflect the status of liver fibrosis. If only one of the four indicators is elevated, fibrosis may have begun to appear in the liver; if two or three indicators are elevated, there is significant fibrosis. Of course, it is difficult to judge the degree of liver fibrosis (ie, the aforementioned liver fibrosis stage) based on the results of serological fibrosis indicators alone. When all fibrosis indicators are increased to varying degrees, especially when the amount of hyaluronic acid (HA) is increased several times, you should consider the possibility of high fibrosis or even early liver cirrhosis. Of course, doctors sometimes combine other information Comprehensive analysis and judgment.

The gold standard for diagnosing liver fibrosis is liver puncture. Observe the liver tissue of the patient under a microscope and perform serological fibrosis index tests. The patient can obtain the exact results of liver fibrosis. Sexual treatment.

Hepatic fibrosis can be improved through treatment. The ant therapy advocated by the Chinese Center for the Prevention and Treatment of Liver Disease has been used to treat the two root causes of liver fibrosis and repair liver cells. It has effectively cured hundreds of patients with liver fibrosis. Clinical verification The effective rate can reach more than 76%. ^[2]