What is Hypertrophy?

An increase in the volume of a cell, tissue or organ is called hypertrophy. The essence is an increase in cell volume. Hypertrophy can be divided into two types: physiological hypertrophy and pathological hypertrophy.

[féi dà]

An increase in the volume of a cell, tissue or organ is called hypertrophy. The essence is an increase in cell volume. Hypertrophy can be divided into two types: physiological hypertrophy and pathological hypertrophy.

Chinese name

Hypertrophy

Foreign name

hypertrophy

Nature

Increased cell volume

Points for

Physiological and pathological hypertrophy

Due to increased functionality,

In nature, hypertrophy can be divided into two types: physiological hypertrophy or pathological hypertrophy.

In terms of reasons, they can be divided into types such as compensatory hypertrophy and endocrine hypertrophy.

Hypertrophy is caused by overloading of the corresponding organs and tissues, which is called compensatory hypertrophy. For example, under physiological conditions, the upper limb bones of weightlifters

Concentric myocardial hypertrophy

Muscle growth and hypertrophy; under pathological conditions, left ventricular myocardial hypertrophy caused by increased myocardial postload or peripheral myocardial function compensation after partial myocardial necrosis of the left ventricle (see the right picture)

Hypertrophy can also be caused by the effect of endocrine hormones on effectors, called endocrine hypertrophy. For example, under physiological conditions, uterine smooth muscle hypertrophy caused by progesterone and its receptors stimulates increased smooth muscle protein synthesis during pregnancy; under pathological conditions, thyroid follicle epithelial cell hypertrophy caused by increased thyroid hormone secretion.

While the parenchymal cells atrophy, the interstitial adipocytes can proliferate to maintain the original volume of the organs, and even cause the organs and tissues to increase in size, which is called pseudohypertrophy.