What Is Non-Diabetic Neuropathy?

Diabetic neuropathy is a metabolic disorder of diabetes and peripheral and central nervous system damage caused by vascular disease. Lesions are mainly found in peripheral nerves, posterior roots, and also in the posterior cord of spinal cord and muscles.

Basic Information

English name
diabetic neuropathy
Visiting department
Endocrinology
Multiple groups
Diabetics
Common locations
Peripheral nerve, posterior root, spinal cord and muscle
Common causes
Unclear, may be related to metabolic disorders such as sugar, fat, phospholipids, and vascular disorders caused by diabetes
Common symptoms
Symptoms of peripheral neuropathy, spinal cord damage, brain damage, and muscle damage

Causes of diabetic neuropathy

The etiology is unknown. It is currently believed to be mainly related to metabolic disorders such as sugar, fat, phospholipids caused by diabetes, and arteriosclerosis of nourishing blood vessels such as peripheral nerves, hypertrophy of middle and outer membranes, hyaline degeneration, and even occlusion.

Clinical manifestations of diabetic neuropathy

In addition to the clinical manifestations of diabetes, such as polydipsia, polydipsia, polyuria, weight loss, fatigue, elevated blood sugar, and diabetes, the nervous system can manifest as:
Peripheral neuropathy
Polyneuropathy is the most common and manifests as bilateral sympathetic sensory disorders, dyskinesias, and ataxia. Cerebral nerve involvement is relatively rare, and there may be one or both abductor and oculomotor nerve paralysis. Vegetation can often be affected by changes in gastrointestinal dysfunction, diarrhea, bladder disorders, impotence, orthostatic hypotension, abnormal sweating, and unstable vasomotor function. The electromyogram showed neurogenic changes and the nerve conduction speed slowed.
2. Symptoms of spinal cord injury
It can be manifested as anterior horn cell damage similar to chronic polio, spinal cord-like (called pseudospinal crest) posterior root and posterior column damage, and posterior and lateral degeneration similar to subacute spinal cord degeneration. These changes are mostly thought to be caused by persistent insufficient spinal cord blood supply caused by diabetic blood vessels.
3. Symptoms of brain damage
There are many causes of encephalopathy in diabetes, which can be caused by high blood sugar, headache, weakness, physical and mental fatigue, excitement, emotional instability, etc., long-term without proper treatment can cause memory loss, mental decline, and can also occur Hypertonic coma, ketotoxic coma, and hypoglycemic coma. In addition, it can also be caused by diabetic angiopathy and cerebral thrombosis, especially multiple lacunar infarction and dementia.
4. Muscle damage
It can manifest as atrophy of pelvic girdle, scapular girdle and proximal limbs.

Diabetic neuropathy

Routine examinations should be done: blood glucose, urine glucose, urine ketone body, etc. and electromyogram, nerve conduction velocity measurement, etc.

Diagnosis of diabetic neuropathy

Diagnosis can be made based on the cause, clinical manifestations, and laboratory tests.

Treatment of diabetic neuropathy

1. Should control diet, control blood sugar, and correct metabolic disorders in the body.
2. B vitamins, folic acid and other drugs can be used to promote the recovery of nerve function.
3. For diabetic cerebrovascular disease can be treated as cerebrovascular disease.
4. Rescue patients with hypertonic coma, ketotoxic coma, and hypoglycemic coma.

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