What Is Pregnenolone?

Pregnenolone is an important intermediate for the synthesis of progesterone, finasteride, etc., and is used in the synthesis of steroidal intermediates and steroidal drugs.

Pregnenolone

Pregnenolone is an important intermediate for the synthesis of progesterone, finasteride, etc., and is used in the synthesis of steroidal intermediates and steroidal drugs.
Chinese name
Pregnenolone
Foreign name
Pregnenolone
CAS number
: 145-13-1
Molecular formula:
C21H32O2
Chinese alias: 5-pregneno-3-ol-20-one; 3b-hydroxy-pregn-5--5--20
White or almost white crystalline powder, odorless
Melting point: 185-193 ° C
Optical rotation: + 28 ° (in ethanol)
Security level: 22-24 / 25
Insoluble in water, soluble in organic solvents such as ethanol, difficult to dissolve in water, and quite difficult to dissolve
Colorless needle-like crystals (recrystallized from dilute ethanol). Is a steroid. Diosgenin, cholesterol, stigmasterol, dehydroepiandrosterone and other steroids are synthesized. Used as an intermediate for the synthesis of sex hormone steroids and adrenal corticosteroids other than progesterone. Its derivative acetate: colorless needle-like crystal, melting point 149-151 ° C. Optical rotation + 22 ° ± 2 ° (in ethanol).

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