What Is an Organic Vapor Respirator?

Propylene glycol ethers and glycol ethers are both glycol ether solvents. Propylene glycol ethers are less toxic to humans than glycol ether products and belong to low toxicity ethers. Propylene glycol methyl ether has a weak ether smell, but does not have a strong pungent odor, making it more widely used and safe. Because it has both ether groups and hydroxyl groups in its molecular structure, it has excellent dissolving properties, suitable volatilization rate and reactivity, and has been widely used.

Propylene glycol ethers and glycol ethers are both glycol ether solvents. Propylene glycol ethers are less toxic to humans than glycol ether products and belong to low toxicity ethers. Propylene glycol methyl ether has a weak ether smell, but does not have a strong pungent odor, making it more widely used and safe. Because it has both ether groups and hydroxyl groups in its molecular structure, it has excellent dissolving properties, and has suitable volatilization rate and reactivity characteristics, so it has been widely used.
Chinese name
Propylene glycol methyl ether
Foreign name
Proprylene glycol monomethyl ether
Alias
Propylene glycol monomethyl ether
Molecular formula
CH3CHOHCH2OCH3
Molecular weight
90.12
Nature
Glycol ether solvents

Propylene glycol methyl ether

Propylene glycol methyl ether product name:

Propylene glycol methyl ether, propylene glycol monomethyl ether,

English name of propylene glycol methyl ether :

Proprylene glycol monomethyl ether, Dow Chemical-Dowanol-PM.
Molecular structure of propylene glycol monomethyl ether [1]

English abbreviation of propylene glycol methyl ether :

PM

CAS: Propylene glycol methyl ether CAS:

107-98-2

Propylene glycol methyl ether molecular formula

CH3CHOHCH2OCH3

Propylene glycol methyl ether molecular weight

90.12

Chemical composition of propylene glycol methyl ether

Ingredient CAS Code Content Harmfulness
1-methoxy-2-propanol 107-98-2 about 75% yes
2-methoxy-1-propanol 1589-47-5 about 25% yes

Propylene glycol methyl ether product specifications

Appearance: colorless transparent liquid
Content: 99%
Moisture: 0.1%
Distillation range: 116-126 ° C
Acidity: 0.02%
Boiling point: 120 ° C
Flash point: 31.1 C (closed cup)
Specific gravity (d420): 0.919-0.924
Viscosity: 20C /1.75mPa.s
Surface tension: (25 ° C) 27.7 mN / m.

Use of propylene glycol methyl ether

[Use 1] Mainly used as solvent, dispersant and diluent, and also used as fuel antifreeze, extractant, etc.
[Use two] 1-methoxy-2-propanol is an intermediate of the herbicide metochlor.
[Use three] As a solvent, dispersant or diluent for coatings, inks, printing and dyeing, pesticides, cellulose, acrylate and other industries. It can also be used as fuel antifreeze, cleaning agent, extractant, non-ferrous metal beneficiation agent and so on. Can also be used as raw materials for organic synthesis.
[Use 4] Propylene glycol methyl ether (107-98-2) is mainly used as an excellent solvent for nitro fibers, alkyd resins and maleic anhydride modified phenolic resins; as an antifreeze agent for jet olefins and as an additive for brake fluids ; Used as a solvent for inks, textile dyes, and textile oils; water-based coatings made from it are widely used in the automotive industry.
[Use five] Propylene glycol methyl ether (107-98-2) is widely used in coatings and cleaning agents. Specific applications as active solvents for water-based coatings; active solvents and coupling agents for solvent-based printing inks; solvents for ballpoint pens and pen inks; coupling agents and solvents for household and industrial cleaners, rust removers, and hard surface cleaners; Solvent for agricultural pesticides; mixed with propylene glycol n-butyl ether for glass cleaner formulations.
[Use six] as a solvent; dispersant or diluent for coatings; inks; printing and dyeing; pesticides; cellulose; acrylic esters and other industries. It can also be used as fuel antifreeze; cleaning agent; extractant; non-ferrous metal dressing agent. Can also be used as raw materials for organic synthesis.

Application fields of propylene glycol methyl ether

Mainly used as an excellent solvent for nitro fibers, alkyd resins and maleic anhydride modified phenolic resins, as an antifreeze for jet fuels and as an additive for brake fluids; mainly as a solvent, dispersant and diluent. As fuel antifreeze, extractant, etc.

Propylene Glycol Methyl Ether

Emergency overview of propylene glycol methyl ether

WARNING ! Flammable liquids and vapors are harmful to the human body if inhaled. It will affect the central nervous system of the human body, and if it is absorbed through the skin or swallowed by mistake, it will also be harmful to the human body. Irritating to skin, eyes and respiratory tract.
Security level
Health Level: 1 (Minor)
Combustion stages: 3 (flammable)
Reaction order: 1
Contact level: 1
Protective equipment: goggles, protective clothing, mask, gloves, Class B fire extinguisher
Storage color code: red (flammable)
Potential health effects

Propylene glycol methyl ether inhalation

Vapors are irritating to the respiratory tract. Vapor concentrations are greater than 100 ppm. Inhaling the vapours can cause unpleasant odors. When the concentration reaches 1000 ppm, the eyes, nose, and throat will be irritated before it affects the central nervous system. Can cause headaches, dizziness, and drowsiness.

Propylene glycol methyl ether ingested

Irritating to the gastrointestinal tract, symptoms include nausea, vomiting, diarrhea, and other symptoms similar to those when inhaled.

Propylene glycol methyl ether skin contact

It can cause irritation, accompanied by erythema and pain, and may be affected by absorption through the skin.

Propylene glycol methyl ether eye contact

Causes irritation, erythema, and pain.
Long-term exposure (exposure):
Prolonged exposure can damage the liver and kidneys.
Deterioration of the situation mentioned earlier:
not found.

Propylene glycol methyl ether emergency method

Propylene glycol methyl ether inhalation:

Move to a place with fresh air. If the patient is unable to breathe, use artificial respiration. If breathing is difficult, provide the patient with oxygen and get medical care in a timely manner.

Propylene glycol methyl ether ingested:

If swallowed, give the patient plenty of water to dilute the solution. If the patient swallows a large amount, or if symptoms are already present, get medical treatment in time. Do not give anything to a person who is not aware of anything.

Skin contact with propylene glycol methyl ether :

Remove contaminated clothing and shoes and immediately rinse with plenty of water for at least 15 minutes. Wash clothing before wearing it again, and wash it thoroughly before wearing it again. Get medical attention if symptoms develop.

Propylene glycol methyl ether eye contact:

Immediately flush your eyes with plenty of water for at least 15 minutes, and occasionally pick up the upper and lower eyelids. If irritation persists, seek medical attention.

Propylene glycol methyl ether fire protection measures

Flammable liquids.
Flash point: 32 ° C (90F) CC
Combustion limit in air (% by volume)
Lower limit: 1.6 Upper limit: 13.8
explosion:
The temperature is above the flash point, and within the aforementioned combustion limits, a mixture of vapor and air explodes. Steam can pass
To the surface of the burning object and the flame will flash back.
Fire extinguishing medium:
Dry powder compounds, foam or carbon dioxide. Water extinguishing may not work. Water spray can cool the fired container, dilute the spill and make it a non-flammable mixture to protect those who prevent leakage and vapor diffusion.
Special fire information:
In case of fire, wear protective clothing. Wear assisted breathing apparatus with a protective mask that may operate under certain pressures or other well-defined pressure modes.

Accidental leakage of propylene glycol methyl ether

Ventilate leaks and spills. Remove all sources of ignition and wear appropriate personal protective equipment, see Section 8 for details. Isolate dangerous areas and evacuate insignificant people and people without protective equipment. Control and cover leaking liquids as much as possible. Use non-sparking tools and equipment. Collect leaking liquid in suitable containers or absorb with inert materials (such as dry sand, dirt, etc.), and place in chemical waste containers. Do not use flammable materials such as sawdust. Do not flush leaked liquid into the sewer. If the leaked or overflowed liquid is not ignited, spray with water to disperse the vapour to protect those who prevent the leakage and flush the leaked liquid from the exposed area.

Propylene glycol methyl ether storage method

Store in a cool, dry, well-ventilated place away from places where there is a danger of fire. It is better to store it outdoors or in a place that is not affected by others, and separate it from things that should not coexist. Containers should be connected and grounded to avoid static sparking. Smoking should be prohibited where the product is stored and used. Use non-sparking tools and equipment. Empty barrels filled with the product may also be dangerous. As there are still residues (vapor, liquid) of the product in these containers, check all warning signs posted on the product barrel.

Propylene glycol methyl ether exposure control

Exposure limit in air:
ACGIH limit value (TLV):
100ppm (TWA), 150ppm (STEL)
ventilation system:
Local systems and / or usual vapor concentrations are recommended to keep employees exposed to air limits. In-situ vapor ventilation is usually chosen because it controls the emission of raw material contaminants. Stop the spread of pollutants into the work area. Please refer to ACGIH document, Industrial ventilation equipment, manual operation is recommended.
Respirator:
If exposure limit is exceeded. When the 10 times exposure limit is exceeded or the maximum concentration is determined by appropriate regulatory agencies or respirator providers, then a semi-face-covered organic vapor respirator is required. When the 50 times exposure limit is exceeded or the maximum concentration is determined through appropriate local regulatory agencies or respirator providers, then a full face respirator is required. For emergencies or situations where exposure standards are not known, use a
A full-face respirator capable of resisting pressure and supplying air. WARNING: Air filter respirators do not protect workers in oxygen-deficient air.
Skin protection:
Wear protective gloves and clean body clothing.
Eye protection
Use chemical safety goggles. Keep water spray and rapid wet-out facilities in the work area.
ACGIH (American Government Industry Association) TLV (recommended value) TWA (minimum concentration value for long-term exposure) STEL (minimum concentration value for short-term exposure)

Propylene glycol methyl ether packaging and storage

Packaging: 190 kg / drum

Propylene glycol methyl ether safety term

S24 / 25Avoid contact with skin and eyes.
Avoid contact with skin and eyes.
S26In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
After accidental contact with eyes, rinse immediately with plenty of water and seek medical advice.
S24 Avoid contact with skin.
Avoid skin contact.

Propylene glycol methyl ether risk term

R10Flammable.
combustible.

Propylene glycol methyl ether substance toxicity

Toxicity data from literature and journals
Numbering
Toxicity type
testing method
Test object
Dosage used
Toxic effect
1
Acute toxicity
Inhale
Humanity
3000 ppm
1. Olfactory toxicity-tumor
2. Behavioral Toxicity-General Anesthesia
3. Gastrointestinal toxicity-nausea, vomiting
2
Acute toxicity
oral
Rat
3739 mg / kg
1. Ototoxicity-blood tears
2. Behavioral toxicity-lethargy
3. Behavioral toxicity-ataxia
3
Acute toxicity
Inhale
Rat
10000 ppm / 5H
Detailed effects are not reported other than lethal dose
4
Acute toxicity
Intraperitoneal injection
Rat
3720 mg / kg
Detailed effects are not reported other than lethal dose
5
Acute toxicity
Subcutaneous injection
Rat
7800 mg / kg
1. Behavioural Toxicity-Impact on Convulsions or Seizure Thresholds
2. Behavioral toxicity-ataxia
3. Lung, chest or respiratory toxicity-difficulty breathing
6
Acute toxicity
Intravenous injection
Rat
4200 mg / kg
1. Behavioural Toxicity-Impact on Convulsions or Seizure Thresholds
2. Behavioral toxicity-ataxia
3. Lung, chest or respiratory toxicity-difficulty breathing
7
Acute toxicity
oral
Mouse
11700 mg / kg
1. Behavioural Toxicity-Impact on Convulsions or Seizure Thresholds
2. Behavioral toxicity-ataxia
3. Lung, chest or respiratory toxicity-difficulty breathing
8
Acute toxicity
Intraperitoneal injection
Mouse
> 500 mg / kg
Detailed effects are not reported other than lethal dose
9
Acute toxicity
Intravenous injection
Mouse
5300 mg / kg
1. Behavioural Toxicity-Impact on Convulsions or Seizure Thresholds
2. Behavioral toxicity-ataxia
3. Lung, chest or respiratory toxicity-difficulty breathing
10
Acute toxicity
oral
dog
5 mg / kg
Detailed effects are not reported other than lethal dose
11
Acute toxicity
Intravenous injection
dog
2 mg / kg
1. Behavioural Toxicity-Impact on Convulsions or Seizure Thresholds
2. Behavioral toxicity-ataxia
3. Lung, chest or respiratory toxicity-difficulty breathing
12
Acute toxicity
oral
rabbit
5700 mg / kg
Detailed effects are not reported other than lethal dose
13
Acute toxicity
Inhale
rabbit
15000 ppm / 7H
Detailed effects are not reported other than lethal dose
14
Acute toxicity
Skin surface
rabbit
13 mg / kg
Detailed effects are not reported other than lethal dose
15
Acute toxicity
Subcutaneous injection
rabbit
5 mg / kg
Detailed effects are not reported other than lethal dose
16
Acute toxicity
Intravenous injection
rabbit
1200 mg / kg
Detailed effects are not reported other than lethal dose
17
Acute toxicity
Inhale
Guinea Pig
15000 ppm / 7H
1. Behavioral toxicity-sleep
18
Chronic toxicity
Inhale
Rat
3000 ppm / 6H / 11D-I
1. Liver toxicity-changes in liver weight
2. Kidney, ureter and bladder toxicity-changes in urine components
19
Chronic toxicity
Inhale
Rat
3000 ppm / 6H / 13W-I
1. Liver toxicity-changes in liver weight
20
Chronic toxicity
Inhale
Mouse
3000 ppm / 6H / 11D-I
1. Liver toxicity-changes in liver weight
twenty one
Chronic toxicity
Inhale
monkey
10000 ppm / 4H / 13W-I
1. Liver toxicity-other changes
2. Liver toxicity-changes in liver weight
3. Nutrition and metabolic system toxicity-weight loss or weight loss rate
twenty two
Chronic toxicity
Inhale
rabbit
3000 ppm / 6H / 13W-I
1. Hematological toxicity-changes in serum composition (such as TP, bilirubin, cholesterol)
2. Biochemical toxicity-inhibit or induce phosphatase
twenty three
Chronic toxicity
Skin surface
rabbit
455 mL / kg / 13W-I
1. Behavioral toxicity-general anesthesia
2. Nutrition and metabolic system toxicity-weight loss or weight loss rate
3. Chronic disease-related toxicity-death
twenty four
Chronic toxicity
Inhale
Guinea Pig
6000 ppm / 7H / 16W-I
1. Behavioral toxicity-general anesthesia
2. Nutrition and metabolic system toxicity-weight loss or weight loss rate
25
Ocular toxicity
Skin surface
rabbit
500 mg
Lighter
26
Ocular toxicity
In the eye
rabbit
500 mg / 24H
Lighter
27
Reproductive toxicity
Inhale
Rat
3000 ppm / 6H, 6-15 days after conception
1. Reproductive toxicity-abnormal development of the musculoskeletal system
28
Reproductive toxicity
Inhale
Rat
3000 ppm / 6H, multiple generations
1. Reproductive toxicity-affects the mother
2. Reproductive toxicity-affecting the live birth index of newborns
3. Reproductive toxicity-physical changes in newborns
[2-15]

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