How Effective Is Clonazepam for Insomnia?
Clonazepam is a drug name, and its pharmacological effects are similar to those of diazepam and nitrazepam, but its anticonvulsant effect is 5 times stronger than the previous two, and the effect is rapid, the effect is stable, and long-term medication can produce tolerance. It is believed that the product is a broad-spectrum antiepileptic drug that can treat various types of epilepsy, but some people do not advocate its use for major epileptic seizures or psychomotor seizures. It is mainly used in children with small episodes, infantile spastic, myoclonic, and inability to move, and the effect is better. Intravenous injection can treat persistent state of epilepsy, and the effect is better than diazepam and phenytoin sodium. Children with frequent seizures often see their effect after the first dose, and reach the maximum effect within 2 weeks.
Clonazepam
- Clonazepam is a drug name, its pharmacological action and
- Chinese name: clonazepam
- Alias: clonazepam, clonazepam, rifampicin, clonazepam, clonazepam
- Foreign name: Clonazepam, Clonopin, Iktorivil, Rivotril, RO 05-4023, Rivotril, Clonopin
- Molecular formula: C15H10ClN3O3 [1]
- The most common adverse reactions are drowsiness,
- Anticonvulsants. The anticonvulsant effect is about 5 times stronger than diazepam or nitrazepam. It is suitable for the control of type epilepsy, and has a good effect on small episodes of absence, infantile spasms, myoclonic and dyskinesia. It is a broad-spectrum antiepileptic drug. [1]
- Yeah
- 1) With alcohol central nervous system inhibitors, opioid analgesics,
- Oral absorption is fast and complete, about 81.2% to 98.1%, and the plasma concentration reaches a peak within 1 to 2 hours. The protein binding rate is about 80%, and the apparent volume of distribution is 1.5-4.4L / kg. High fat solubility, easy to cross the blood-brain barrier, oral effect for 30 to 60 minutes, the effect is maintained for 6 to 8 hours. Almost all are metabolized in the liver, and the metabolites are excreted in the urine in free or bound form, and less than 0.5% of the oral amount is excreted in the original form within 24 hours. t1 / 2 is 26 to 49 hours.