How Effective Is Imiquimod for Warts?

Imiquimod is an imidazoquinoline compound. Molecular formula: C14H16N4, is a small molecule immunomodulator. Its mechanism of action for treating external genital / perianal warts is unknown. This product does not have direct antiviral activity, nor does it cause direct, non-specific cytolytic destruction. However, preclinical studies suggest that this product may produce antiviral activity by inducing cytokines including INF- in the body. The clinical relevance of these findings is unknown.

Imiquimod

Common name: Imiquimod

English name: Imiquimod

Phonetic script (Hanyu Pinyin): Mikuimote

The main ingredients of this product are: The main ingredient of this product is imiquimod, its chemical name is: 1-

This product is a cream based white cream.

toxicology

Rat and mouse

There are no available pharmacokinetic data for dermal administration. Studies have shown that topical application of a 5% imiquimod emulsion has little systemic absorption through the skin.

(1) Imiquimod is administered 3 times a week (Monday, Wednesday, Friday or Tuesday, Thursday, and Saturday). Use the medicine reasonably under the guidance of a doctor to give the best effect of this product. It is recommended to wash your hands before and after use. Imiquimod is more tubular (

Local skin reactions such as:

(1) Those who are allergic to imiquimod or excipients;

(2) Not recommended for HPV infection in the urethra, vagina, cervix, rectum or anus;

(3) It is not recommended to use 5% imiquimod cream immediately after other drugs or surgical treatment; nor is it recommended to use 5% imiquimod cream in combination with other drugs for treating external genital warts.

(1) It should be used after being instructed by a doctor. This product is for external use. Avoid contact with eyes.

(2) The treatment site does not need to be covered with a bandage.

(3) 5% imiquimod cream can reduce the contraceptive effect of condoms, so sexual contact should be avoided when using the drug.

(4) For male patients with long foreskins, there is no recommended treatment plan, so it is not recommended for such patients.

(5) Reactions such as erythema, exfoliation / exfoliation, erosion and edema are common at the site of application and surrounding skin. Most skin reactions are mild and moderate, and severe skin reactions should be reported to your doctor as soon as they occur.

(6) Patients need to know that new warts may grow during treatment because 5% cream cannot cure warts. People older than 75 years of age or less than 18 years of age have no experience with medication.

(1) This product is not recommended for pregnant women.

(2) It is not known whether there is drug secretion in breast milk after topical application of imiquimod, and it is not recommended for lactating women to use this product.

No medication experience in patients under 18 years of age.

It is generally not possible for humans to use 5% imiquimod emulsions because they are absorbed very little by the skin. Animal experiments have confirmed that the lethal dose of rabbit skin is greater than 1600 mg / m2. Sustained overdose of topical 5% imiquimod emulsion can cause severe local skin reactions. Hypotension is a side effect of multiple oral administration doses> 200mg in clinical practice. Hypotension occurs only orally or intravenously. ^[1]

5% Imiquimod Cream, 3g / box

Packed in aluminum foil.

Store below 25 ° C and avoid freezing.

Valid for one year

National Medicine Standard H20031230, National Medicine Standard H20040285

Mingxin Pharmaceutical Co., Ltd. Imiquimod Cream Pack 250mg: 12.5mg × 4 bags = 298 yuan

Hubei Keyi Pharmaceutical Co., Ltd. Imiquimod cream tube 0.15g: 3g RMB 298; 0.25g: 5g RMB 488

US 3M company is $ 170