What are acetylcholine inhibitors?
acetylcholine inhibitors are chemical compounds that compete and counteract the functioning of the neurotransmitter acetylcholine. As a result, it suppresses the activity of the parasympathetic nervous system. The effects of acetylcholine inhibitors include reducing gastrointestinal activity, increasing urine retention, reducing the airway narrowing and accelerating heart rate. Many of these clinical effects are useful in the treatment of various diseases. Neurotransmitters are chemical compounds that transmit information from nerve cells to body tissues. They are released in response to an electrical signal from nerve cells and bind to receptors either on cell surfaces or in cells. Oh plays a decisive role in the central nervous system, which includes the brain and spinal cord as well as in the peripheral nervous system.
This neurotransmitter is also important because it helps to perform the activities of the parasympathetic nervous system. This system controls the body's automatic functions at a time of safety. It works oppositea nice nervous system that is responsible for the reaction of a "fight or flight" observed at a time of danger. Normal activity of the parasympathetic nervous system allows the body to "relax and spend" and therefore promotes reduced heart rate, increased gastrointestinal activity and eye narrowing.
by competition with ACH, acetylcholine inhibitors reduce the effect of the parasympathetic nervous system. Therefore, the effects of these drugs change some natural functions of the human body. They cause pupils' dilation, increased heart rate, constipation, urine retaining, loss of sweating and dry mucus membrane.
acetylcholine inhibitors have a wide range of clinical applications. They can be used to treat respiratory disorders such as asthma and chronic obstructive lung disease because they reduce respiratory secretions and minimize respiratory spasms. Anticholinergic agents can be controlled by an excessively active bladder,Because they promote urine retention. Slow heart rate, known as bradycardia, can also be treated with these drugs.
Compounds that have an activity inhibitor acetylcholine have been used for various purposes for hundreds of years. The Belladonna plant contains atropine chemical, a acetylcholine inhibitor. The Italian ladies once applied the extracts of this plant to their eyes because it caused pupils to dilation. They thought it increased their physical attraction.
A wide range of acetylcholine inhibitors, also known as anticholinergic agents, still have important functions. Atropine in a more refined form is still used in Modern Times. Other anticholinergic agents include ipratropium, scopolamine, oxybutynin and tolterodin.