What are the different side effects of sulfasalazine?
sulfasalazine, also known as azulfidin® or salazopyrin, creates a wide range of side effects that correlate with antibacterial, anti -inflammatory and immunosuppressive properties of the drug. Side effects can also be created or strengthened by interactions with certain drugs. Some side effects include colored urine, nausea, increased likelihood of blood disorders, meningitis and hallucinations. Among the side effects of sulfasalazine commonly used to treat rheumatoid arthritis and ulcerative colitis
One of the common and harmless side effects of sulfasalazine includes orange -yellow color urine; This side effect may also spread to skin coloring. As with many antibiotics, people who take medication usually experience abdominal discomfort, nausea, vomiting and diarrhea. Many individuals also tolerate anorexia, headaches, oxidized hemoglobin and reduced sperm number. Some symptoms of a stomachThey can be minimized by enterically coated tablets. Persons can also see the development of different types of skin rash.
The anti -inflammatory properties of the drug improve bowel inflammation for those with colitis, but together with immunosuppressive activity, signs of developing infections could mask until people experience sore throat or fever. The immunosuppressive effect of the drug could disrupt chemicals, enzymes and cellular activity that create natural immune responses. Vedlejší účinky sulfasalazinu v této oblasti mohou zahrnovat potlačení kostní dřeně, ovlivňující červené a bílé krvinky a potenciálně způsobující četné typy poruch krve, které mají za následek anémii.
Higher concentration drugs usually occur in areas of the body containing pure fluid and connective tissue. Increased concentrations also generally accumulate in the liver and in the intestine. Does not participate in the effects of sulfasalazine that appear at z zAP -Central nervous system apartment may include drowsiness, insomnia or depression, convulsions, hallucinations and meningitis. Nerve tissue involvement can cause inflammation and pain along with hearing disorders, hearing loss or lack of physical coordination. The side effects that occur due to liver engines include signs of hepatitis correlation, liver damage or liver failure.
There are more than 20 drugs that can be contraindicated by sulfasalazine. Sulfasalazine usually reduces the absorption of folic acid and digoxin, resulting in anemia and abnormal pulse. Persons who have sensitivity to sulfa drugs or aspirinstons. These reactions include asthma and other lung disorders, skin reactions, heart and vascular anomaly and liver symptoms. Persons who have different health conditions can also experience increased severity of symptoms. Before receiving sulfasalazine, it is important to discuss all current medicines or conditions with a doctor.
drugs are usually not recommended by uindividuals with kidney or liver disease. Sulfasalazine is also generally not used in patients with gastrointestinal or kidneys or in pregnant women due to possible congenital defects. Persons who have blood disorders or lack of glucose-6-phosphate dehydrogenase, commonly referred to as G6PD, also experience impaired symptoms.