What Are the Medical Uses of Montmorillonite?

Montmorillonite is a layered mineral composed of extremely fine-grained hydrous aluminosilicate, also known as colloidal kaolinite, microcrystalline kaolinite. It is a main component of bentonite that is altered by igneous rocks such as volcanic condensate in an alkaline environment. ^[1]

The name of Montmorillonite comes from the place where it was first discovered-Montmorillon, France. The montmorillonite subfamily belongs to one of the smectite minerals (the other subfamily is saponite), which is an important clay mineral, which is generally block or earthy. Molecular formula (Na, Ca) 0.33 (Al, Mg) ₂ [Si ₄ O ₁₀ ] (OH) ₂ · nH ₂ O, with

Monoclinic system; C32h-C2 / m; a0 = 0.523 nm, b0 = 0.906 nm, c0 = 0.96 2.05 nm. For example, when there are one, two, three, and four water molecular layers between the calcium montmorillonite layers, their c0 values are 0.96 nm, 1.25 nm, 1.55 nm, 1.85 nm, and 2.05 nm respectively; is nearly 90 °. TOT type, octahedral type structure.

Montmorillonite is mainly formed by the weathering of basic igneous rocks in an alkaline environment, and some are the products of the decomposition of volcanic ash deposited on the sea floor. Montmorillonite is the main component of bentonite. Bentonite is produced in many places in China, such as Liaoning, Heilongjiang, Jilin, Hebei, Henan, and Zhejiang. The montmorillonite deposits of industrial value in China are mostly produced in the Mesozoic volcanic rock series.

Generally speaking, the appearance of montmorillonite mostly refers to bentonite raw ore. The bentonite raw ore is often soil-like cryptocrystalline block, and it is a small scale under electron microscope. Generally speaking, the microstructure of montmorillonite is mostly the crystal structure of montmorillonite.

Water swelling is its characteristic. Exact identification requires the combination of X-ray analysis, thermal analysis, chemical analysis, and infrared spectroscopy.

The analysis of montmorillonite data by infrared spectrum analysis technology is as follows:

The montmorillonite organic complex is made from its cation exchange properties, which is widely used in high-temperature grease, rubber, plastics, and paints; and its adsorption properties are used for edible oil refining and detoxification, oil purification, nuclear waste treatment, and sewage treatment; It can be used as a foundry sand binder with its cohesiveness; it can be used for drilling mud with its dispersibility. Because many properties of sodium montmorillonite are better than calcium montmorillonite, cation exchange performance of montmorillonite is often used for modification treatment to transform calcium montmorillonite into sodium montmorillonite. Montmorillonite is widely used in medicine. It can be used as a pharmaceutical carrier to play the role of a controlled release agent. In the field of medicine, montmorillonite has a mature product. It has almost become synonymous with montmorillonite and has an antidiarrheal effect. Montmorillonite has a good application in livestock (pig, rabbit) breeding, especially the yellow and white pheasants of piglets and suckling pigs, and the thinning of rabbits has preventive effect. In view of the characteristics of montmorillonite, it can also be used as the best The first choice of feed mold remover. Montmorillonite, as a supplementary feed additive, has been widely used in livestock and poultry breeding abroad due to its natural properties and composite functions. In the United States, montmorillonite is used as animal feed for 2.14% of total consumption, and in Armenia it already accounts for 5.47%. It can not only compensate animal nutrients and improve production performance of livestock and poultry, but also regulate CP flow in animals and prevent digestive tract. Disease has a role.

Smectite principle

The sample was modified by boiling with ammonium chloride, washed with water, and then added with potassium chloride solution to replace the exchanged ammonium ions, and then added formaldehyde. The replaced ammonium ions and formic acid were used to generate hydrochloric acid. Standard hydrogen was used. Titrate the sodium oxide solution and calculate its ammonium uptake.

Montmorillonite analysis steps

Weigh 1.000 g (accurate to 0.001 g) of the sample into a 250 mL beaker, add 1.0 mL of mol / L ammonium oxide solution (4.1.7) 50 mL and a little pulp, boil on a hot plate and keep it warm for 30 min. Remove, filter with slow speed filter paper, and wash with boiling 1.0 mol / L ammonium chloride solution (4.1.7) until the outflowing solution is free of calcium and magnesium ions (check method, add a few milliliters of atmosphere in a small beaker -Ammonium chloride buffer solution (4.1.10) and 1 drop of acid chrome blue K indicator, accept some filtrate, if the solution does not change to red, it means it has been washed). Then wash with warm water until no chloride ions (silver nitrate solution (4.1.11) check), rinse the tail of the funnel with water to prevent a small amount of ammonium chloride from contaminating. The funnel is replaced by a clean 250 mL beaker. 1.0 mol / L potassium chloride solution (4. 1.8) 80 mL. After the solution in the funnel is finished, add 15 mL of formaldehyde solution (4.1. 9) to the beaker, using phenolphthalein as the indicator, use 0.1 mol / L sodium hydroxide standard solution (4. 1.12) was titrated to red. Then take a 1.0 mol / L potassium chloride solution (4.1.8) in the beaker. If the solution red does not fade in 30s, it means the end point has been reached. If the red color fades, the titration should be repeated until the red color is stable. Calculate the result with the total volume of the sodium hydroxide standard solution consumed in three titrations.