What factors affect a sufficient dose of Alendronate?
A sufficient dose of Alendronate is affected by many factors, including the condition used for treatment, whether the drug is used or for treatment and how often the patienbt wishes to take the medicine. Patients may decide to take Alendronate every week or daily, which affects what is classified as a sufficient dose. The normal, daily dose for osteoporosis is 10 milligrams (mg) orally per day and the weekly dose is 70 mg orally per week. When the drug is used for other conditions such as Paget's disease, the recommended dose of Alendronate increases to 40 mg daily. This is the primary use of the drug, and therefore most patients will be at this dose. This can be reduced to 5 mg daily if osteoporosis was caused by glucocorticoids. In menopausal women with osteoporosis induced by glucocorticoid with reduced dosage should only be given if the patient currently does not take estrogen.
different conditions require the treatment of another dose of Alendronate. Another most common condition that is used for treatmentIt is Paget's disease. This requires treatment of much greater dose than osteoporosis, 40 mg daily. Patients should take this daily dose for approximately six months to clarify the condition, and this regime should be repeated if the patient suffers from relapse.
It is also possible to take Alendronate as a preventive remedy for osteoporosis. This can be done in the case of high -risk patients such as after menopause. The required dose of Alendronate to prevent osteoporosis is used 5 mg per day, half the amount required to treat osteoporosis.
For the treatment or prevention of osteoporosis, patients may decide to give a dose of Alendronate daily or we or myeks. The total amount of dosage is the same during the week, but the individual doses differ considerably. If the patient uses one weekly dose of Alendronate for osteoporosis, the dose would be 70 mg compared to 10 mg doses needed for daily treatment.Doctors often allow patients to choose the frequency of their treatment.
Alendronate is part of a drug class called bisphosphonates used to prevent osteoporosis and other degenerative bone conditions. Bone cells are constantly removed and replaced by cells called osteoblasts and osteoclasts. Drugs such as Alendronate stop the effects of osteoclasts that remove bone material. This helps to fight conditions such as osteoporosis, increasing bone density.