What Is the Relationship Between Carbidopa and Levodopa?
Carbidopa-levodopa Indications: Carbidopa-levodopa is used to treat Parkinson's disease and Parkinson's syndrome. [Precautions]: Common dance-like movements, muscle twitches, and eyelid spasms.
Carbidopa levodopa
(Carbidopa-L-Dopa)
Right!
- Carbidopa-levodopa Indications: Carbidopa-levodopa is used to treat Parkinson's disease and Parkinson's syndrome. [Precautions]: Common dance-like movements, muscle twitches, and eyelid spasms.
- [Indications]: Carbidopa-L-dopa is used to treat Parkinson's disease and Parkinson's syndrome.
[Precautions]: Common dance-like movements, muscle twitches, and eyelid spasms. Other serious adverse reactions include mental changes, arrhythmias, upper gastrointestinal bleeding, hypertension, white blood cell and thrombocytopenia, and laboratory abnormalities including elevated serum alanine aminotransferase, elevated bilirubin, and elevated blood urea nitrogen. higher. Carbidopa-levodopa is contraindicated in patients with narrow-angle glaucoma and allergic reactions to carbidopa-levodopa. Because levodopa can initiate malignant melanoma, patients with a history of melanoma are contraindicated. Carbidopa-levodopa is also prohibited from being used in combination with monoamine oxidase inhibitors. Breastfeeding women are prohibited. Patients with severe heart, lung, liver, kidney disease and neurosis and open angle glaucoma should be used with caution. Vitamin B6 can accelerate the peripheral metabolism of L-dopa to dopamine. Symptomatic orthostatic hypotension can occur in patients who are already receiving antihypertensive medications after adding carbidopa-levodopa. At this time, the dose of antihypertensive drugs needs to be reduced. Carbidopa-levodopa in combination with tricyclic antidepressants may cause hypertension and dyskinesias, and should be noted. After the combined application of phenothiazine, bupropion, sodium phenytoin, and papaverine with levodopa, there have been reports of reduced efficacy of levodopa.
[Usage and dosage]: Oral: The initial dose is Xinningmei 25/100 (one tablet) 3 times a day until the dose is increased to 8 tablets Xinningmei 25/100 daily. Maintenance amount can be replaced with Xinningmei 25/100 or 12.5 / 50 (1 tablet) Xinningmei 10/100. The maximum dose is 25/250, 3 to 4 times a day, 1 tablet each time, and the maximum dose does not exceed 8 tablets per day.
[Packaging]: Tablet: Xinningmei 25/100 contains 25mg methyldopazide and 100mg of levodopa, Xinningmei 25/250 contains 25m *