What is chymopain?

Chymopapain is a proteolytic enzyme that comes from the latex of the tropical tree known as Carica Papaya. It is used for injections for herniated discs in the spine. The procedure, called chemonucleolysis, was first used in 1965 and effectively dissolved part of the spinal cord by means of an enzyme or a derivative product of chymodiactin. The substance that has been given in the operating room during the treatment of the disk is supplied by an injection once the patient is provided with local or general anesthetics. The compound dissolves part of the affected disc to relieve the pressure of the nerve and also reduce the related pain. The most commonly reported reactions such as stomach, headache, back pain, dizziness and rear convulsions. It is also possible to experience leg pain and tingling, as well as dull legs and fingers after the procedure. Thepreas of other allergies and diseases may worsen the response to chymopaine and serious reactions may include rash, difficult breathing and anaphylactic shock. As a result, one percent of all people who are injected by anaphylaxis.

There are other ways that chymopain can be introduced into the body. Any kind of food based on papayas, such as pineapple or drinks that include exotic fruits, may include compounds that have a similar composition. Compounds such as papain and caracaine are closely related, so the exposure can cause them the same reactions as if chymopain is injected directly into the body. Sensitivity to papain increases the likelihood of an allergic reaction if proteolytic enzyme is used.

It is important to tell a doctor if there is any known allergy to papain or some food or substance based on papaya. Medicines that include Chymopaind with caution in pregnant women. It is also not known whether drugs are transferred to breast milk and it is strongly recommended to discuss it with a doctor before breastfeeding.

Chymopapain is synthesized in the latex of the Carica Papaya tree when it is damaged, and the enzyme matures a few minutes later. Among others lLate in latex papaya includes chitinase and glycyl endopeptidase. The enzyme used for disc treatment is so similar to papain that they share 126 identical amino acids. It is strongly recommended to publish whether an allergy to papaya is present when considering the treatment of a hernified disk with Chymopain.

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