What is Kolistin sulfate?
colistin sulfate is a drug that has antibiotic properties and is therefore often used to treat bacterial infections. The form of this compound is naturally produced by some bacteria in nature as a defense mechanism against other species. His discovery led to Colistine adapted for healing use. Only certain types of bacteria are affected by this drug, and is therefore generally taken for intestinal infections and sometimes for infections on the skin surface. It is usually used only in situations of the last resort, against germs that have proved resistant to other antibiotics.
bacterial cell membranes have ions that help maintain these barriers intact. Kolistine sulfate can replace these ions, open the membrane and dissolve it. Liquids can then enter the affected bacteria that destroys it. Changes in the ion area of this drug have led to two distinguishable forms of this drug, sulphate colistine and kolistimethatate sodium. Each zslenky can be OPTimally effective against different types of bacteria.
Like other medicines, the right dose of sulfate colistine must be used to provide benefits to minimize side effects. Often a dose of colistin equals 1 and 1.5 mg for each 2.2 pound (1 kilogram) of body weight. Otherwise healthy children and adults can use this dose every eight hours, but people with kidney damage can only take their doses one to twice a day. Sometimes doses are administered in measurement called international units. In this case, one to two million units is usually considered a full dose for treatment.
In most cases, colistin sulphate is used in injection form, either intramuscular (IM) or intravenous (IV) injection. This form of drug can be combined with other IV solutions, such as salt solution, but usually not with other medicines. Local preparations of this of some areas, howeverRO treatment of skin infections, and these may contain colistin mixed with other drugs such as hydrocortisone.
As already mentioned, there may be adverse effects in using this drug, occasionally on therapeutic levels. The side effects of colistine sulphate may include nausea, tingling, or dull feelings in the hands and feet and respiratory problems. High doses of this drug were associated with nerve and kidney damage. In general, the risk of this damage is small at lower doses, although these doses are used for months at a time.