What Is Induction Therapy?

Induction chemotherapy, also known as neoadjuvant chemotherapy, refers to chemotherapy used before radiotherapy, which can reduce tumor burden and all kinds of clinical symptoms caused by tumors in a short period of time, improve blood supply and improve radiosensitivity, and also have certain effects on subclinical metastases. Role. Commonly used platinum-based chemotherapy.

Induction chemotherapy

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Induction chemotherapy, also known as neoadjuvant chemotherapy, refers to chemotherapy used before radiotherapy, which can reduce tumor burden and all kinds of clinical symptoms caused by tumors in a short period of time, improve blood supply and improve radiosensitivity, and also have certain effects on subclinical metastases. Role. Commonly used platinum-based chemotherapy.

Chemotherapy uses chemical drugs to kill

Anti-vomiting drugs should be added before applying chemotherapy. If a large dose (60-100 mg per square meter) of cisplatin is used, it should be "hydrated", given a dehydrating agent such as mannitol, sufficient rehydration (not less than 2000 ml), maintaining electrolyte balance, and during hydration. Monitor urine volume, electrolytes and renal function. Nasopharyngeal carcinoma induction chemotherapy is generally suitable for 2 courses. After chemotherapy, radiotherapy should be performed as soon as possible to reduce the chance of tumor cells accelerating re-proliferation and causing a rebound effect of the tumor. Induction chemotherapy should avoid the use of single-agent or low-response chemotherapy regimens, because ineffective induction chemotherapy can not only delay radiation therapy and cause tumor cells to accelerate re-proliferation, reduce the local control rate, but also make chemotherapy-insensitive tumor cells A transfer occurred.