What is the minimum bactericidal concentration?
Minimal bactericidal concentration (MBC) usually applies to antibiotics. It is the rate of how much a particular antibiotic is needed to kill bacteria. Laboratory analysts can assess MBC drugs for bacterial infection to help physicians in the treatment of the patient. Antibiotics
are drugs that adversely affect bacteria. Some bacterial species are sensitive to certain antibiotics, but the physician may not know which dose of antibiotics is appropriate or may not know whether the infection is treated. Low dose of the drug can inhibit bacteria growth and therefore prevent impairment of infection. This dose concentration is called minimal inhibitory concentration (MIC). The dose of antibiotics does not kill the bacteria already present at the concentration of MIC. This information is useful to doctors, the WHO may not want to expose your patient unnecessary levels of drugs in case of side effects. The known minimum bactericidal concentration can also lead to a shorter antibiotic course.
bacteriostatic antibiotics are those that usually inhibit further growth of bacteria, and drugs that usually kill bacteria at a normal dose are called bactericidal. Medicines that are bacteriostatic usually have a microphone that is much smaller than MBC, and bactericidal drugs generally have similar MIC and MBC. MIC and MBC can be determined in the laboratory, although many antibiotics are known to MBC expressed at the recommended doses of manufacturers that doctors can use to treat patients.
A common laboratory method to determine a microphone for a particular bacterial strain uses test tube and bacterial culture. Many pipes receive nutrient base. Then a microbiologist makes diluosobs of antibiotics, each diluted than the previous one. Inserts individual dilution into tubes and adds bacteria samples, causing infection.
After incubation of solutions in a controlled and heated environment for the period of time, the analyst checks each tube. MIC AntibiOtky is a tube that holds the lowest dilution of a drug that shows no bacterial growth. In order to determine the minimum bactericidal concentration, the analyst can place a sample from inhibited tubes on the growth medium. MBC of antibiotics is represented by the lowest dilution that shows no growth on agar plates.