What is Pentoxifyyline?
Pentoxifyline, known by brands such as Pentoxil® and Trentental®, is a medicine that increases blood flow in the body. This medicine is primarily used in the treatment of intermittent claudications, where people develop muscle convulsions and pain at the ends due to partially preventing blood. Pentoxifylline improves microcirculation, ensures that the muscles gain enough nutrients and oxygen and sometimes add to painful convulsions and stiffness to make patients feel more comfortable. Peripheral arterial disease (PAD) is a common culprit for intermittent claudication, although other conditions may be included.
The exact mechanism of this drug is not fully understood. It appears to inhibit the activities of some enzymes to reduce blood viscosity and improve circulation when blood vessels are narrow or partially impassable. This feature caused the drug to be useful for the treatment of vascular dementia, where blood into the brain decreases neurological problems and the drug can be used to treat patients with this condition.
side effects in patients on PentoxiFylin varies. Some common problems are dizziness, nausea, insomnia and headaches. Some patients notice their vision changes. More seriously, the medicine can cause problems with jathers and may be dangerous to the heart in some patients. People who notice the persistent weakening side effects should contact a doctor. Signs of jaundice, indicating acute dysfunction of the liver, should be solved as quickly as possible.
This drug was associated with the development of congenital defects. For this reason, pregnant women are not recommended. The effects on breast milk are not known and some doctors are recommended against its use in nursing mothers. The doctor may decide that the benefits of the drug outweigh the risks and continue to continue this during pregnancy if the patient is willing to be carefully monitored for signs of poor reactions to the drug. Alternative medicines and therapy can be considered nonly in order to determine if the bad circulation can be managed by safer means.
Pentoxifylline is only available according to the regulation and may interact with blood thinners and other medicines that are known to have diluted for blood, even if it is not their primary purpose. Patients taking such medicines are exposed to increased risk of excessive bleeding and pentoxifylline may increase this risk and potentially expose patients of easy bruises, which is anemia caused by bleeding problems and internal bleeding, which is a potentially dangerous complication. Patients with blood disorders and patients on anticoagulants should talk to their doctors before starting the therapy with pentoxifylline.