What Is Phenylephrine?

Phenylephrine is a synthetic adrenaline-like drug.

Phenylephrine

This entry lacks an overview map . Supplementing related content makes the entry more complete and can be upgraded quickly. Come on!

Phenylephrine is a synthetic adrenaline-like drug.

[Aka]

Phenylephrine, neoforin, phenylephrine, neosympathol, Phenylephrine, Neosynephrine, Neophyrin, Mesaton

It can be used to increase systemic pressure and improve the symptoms of acute episodes of tetralogy of Fallot.

Chinese name: Phenylephrine
Aka: Neoforin, phenforin, neosymbol
Use: Intramuscular injection

Dosage form: Injection: 10mg / 1ml eye drops: 1-2.5%
CAS number: 61-76-7 ^[1]
EINECS number: 200-517-3 ^[1]
Melting point: 140-145 ° C ^[1]

effect

The main excitement of a receptor is weaker and longer-lasting than norepinephrine. It can be maintained for 1 hour by intramuscular injection and 20 minutes by intravenous injection, with less toxicity. It can make the vagus nerve reflex and slow down the heart rate by constricting blood vessels and increasing hypertension. It can be used clinically for paroxysmal supraventricular tachycardia. When applying, pay attention to control the systolic blood pressure not to exceed 21.3KPa (160mmHg). Phenylephrine can also excite pupil dilation muscles, making the pupils dilate, the effect is relatively weak, and the duration is short, generally does not cause elevated intraocular pressure (in elderly iris corneal stenosis may cause elevated intraocular pressure) and adjustment paralysis. Use its 1.0% ~ 2.5% solution to drop the eye, and it can be used as a fast and short-acting pupil dilatation drug during fundus examination.

usage

Intramuscular injection: 5-10mg / time, once every 1-2 hours. Extreme amount 10mg / time, 50mg / day.

Intravenous injection: 0.25-0.5mg / time, diluted to a concentration of 0.02%. Extreme 0.5mg / time, 2.5mg / day.

Intravenously, slowly drip into 500ml diluted with 5% glucose solution with 10-20mg.

[Formulation]

Injection: 10mg / 1ml

Eye drops: 1-2.5%