What Is the Relationship Between Duloxetine and Fibromyalgia?
Duloxetine hydrochloride, chemical substance, Chinese chemical name (S)-(+)-N, N-dimethyl-3- (1-naphthyloxy) -3- (2-thiophene) -propylamine hydrochloride salt
Duloxetine hydrochloride
- Duloxetine hydrochloride, chemical substance, Chinese chemical name (S)-(+)-N, N-dimethyl-3- (1-naphthyloxy) -3- (2-
- Chinese chemical name: (S)-(+)-N, N-dimethyl-3- (1-naphthyloxy) -3- (2-
- Appearance: white or off-white crystalline powder
- Solubility: slightly soluble in water, easily soluble in methanol,
- Duloxetine hydrochloride (Cymbaha, hereinafter referred to as
- In August and December 2004, the United States and the European Union respectively ratified
- In long-term studies, a comparison of adverse events in early and later reported treatments showed that long-term treatment did not cause special adverse events. In summary, since duloxetine was first marketed in the United States in 2004, it has been approved to treat severe depression, generalized anxiety, women's stress urinary incontinence, and diabetic peripheral neuropathic pain and Fibromyalgia is one of the five neurologically related diseases. Due to the good safety and tolerability of duloxetine, coupled with accurate and rapid efficacy, simple and convenient medication regimen, and few (small) side effects, it has been rapidly and widely accepted clinically. Global sales in 2008 have reached 2.7 billion US dollars. Duloxetine is undergoing a number of studies for the treatment of various chronic pains, including osteoarthritis-related pain and chronic low back pain. The future clinical use is expected to be further expanded. The market potential is huge and deserves clinical and market attention. The changes in vital signs and weight during long-term treatment of duloxetine are not different from those of previous treatments. In the acute phase, it will cause a slight increase in blood pressure and heart rate. The weight will decrease during early treatment, and it will increase slightly during subsequent long-term treatment.