What is hexaniacinate inositol?
by combination of six -sided molecules of inositol carbohydrate and six nicotine molecules, niacin forms, chemists create inositol hexaniacinate, a compound often used as a dietary supplement. While one substance can be found in a series of foods, a combined higher dose supplement is often considered to be a change in cholesterol. Research also shows that the compound has beneficial effects for those suffering from peripheral vascular disorders. The compound is generally subject to metabolism more slowly than niacin itself, thereby inhibiting sudden vasodilation and flushing effects.
Scientists are divided into the effectiveness of the cholesterol compound. While some believe that inositol hexaniacinate brings satisfactory results, others suggest that the compound is not effective if it is not performed in high doses, which can cause side effects similar to niacin use itself. Combined with inositol, hexaniacinate metabolism may last 10 hours or more, which prevents flushing. Scientists thinkOnce consumed, inositol hexaniacinate breaks back to inositol or myo inositol and nicotine acid. Others argue that this metabolization may or may not occur and suggest that the combination will not allow sufficient free -flowing nicotinic acid.
health care providers can prescribe hexaniacinate inositol at doses of 1,500 milligrams to 4,000 milligrams per day, taken as two to four divided doses. Scientists believe that the compound causes beneficial effects in persons diagnosed with certain peripheral vascular disorders, including intermittent claudication and Raynaud's syndrome. Persons suffering from intermittent claudications experience pain while walking due to insufficient circulation in the legs. Raynaud's produces alternating warm and cold feelings in the hands along the wizena color and is also associated with impaired circulation.
Flushing occurs when bloodThe blood vessels quickly expand and create a rush of blood flow that experiences some as a sudden overall warm feeling, followed by redness of the skin, chills and dizziness. Some individuals get in front of their breath, have increased heart rate and experience rich sweating. Inositol hexaniacinate in such high doses can cause flushing, skin rashes and itching, along with gastrointestinal symptoms that include nausea, vomiting or diarrhea. High doses can also increase blood uric acid levels and blood glucose levels. Because the liver metabolizes hexaniacinate inositol, some experience the toxicity of the liver.
niacin generally reduces cholesterol inhibition of tissue fats. The fats cannot pass through the bloodstream into the liver to convert to low density lipoproteins (LDL) or poor cholesterol. As the number of LDL decreases, lipoproteins with high density (HDL) increase. HDL, or good cholesterol, flows through the blood collection of cholesterol and returns it to the liver to removefrom the body. Niacin is usually quickly metabolised and culminates in a relatively short period of 30 minutes to one hour.