What is the calcitonin receptor?
Calitone receptor is found in thyroid cells that produce calcitonin. This receptor binds the calcium ions in the blood that increases because calcium is absorbed from food. This process releases calcitonin hormone, which prevents calcium levels from being built too quickly by preventing the absorption of calcium ions through the small intestine and releasing bone cells. These receptors are classified as receptors associated with class B, G (GPCR) protein and are similar to the receptor of the calcitonin receptor and the body hormone receptor. This hormone is synthesized in parapholikular cells or C cells inside the thyroid gland. Calitonine is a 32 amino acid long substance that belongs to the hormone family, including amylin, an insulin product in the pancreas; Peptide related to Calcitonine (CGRP), dilator of blood vessels; and adrenomedullin, which also regulates dilatacikrevní vessels. CGRP stimulation does not cause a change in vascular function, heart rate or blood pressure and itself toAlcitonin inhibits the decomposition of bone cells with osteoclastic cells. This in turn prevents the transmission of calcium from bone fluid into the bloodstream.
In addition to the calcitonin receptor function, calcitonin can be used as a medical treatment of conditions such as osteoporosis. It can be administered by inhalation and a commercially available nasal spray is available for this purpose. Calcitonin is digestible, so it is not an effective method.
Hyperparathyroidism, a condition in which receptors cannot prevent calcium from being built in building a distinction is a disorder involving calcitonin receptor. Another type of receptor mutation causes hypoparathyroidism, leading to low calcium in the blood and high calcium levels in the urine. Autoimmune disorders, tumors, injuries and inherited defects can also negatively affect the function of the calcitonin receptor.
Many states that affect receptors can be treated with calcium accessories and also with calcitarol, variantVitamin D. Calitone receptor has a direct effect on bone health and its condition can be monitored by measuring deviations of calcium calcium levels from normal. This can help the detection and successful treatment of thyroid disorders and other health conditions.