What Is Aminoacyl tRNA?

Aminoacyl- tRNA (Aminoacyl-tRNA) is a tRNA (also known as "transfer ribonucleic acid") that binds to its corresponding amino acid. Its role is to pass amino acids into the ribosome, where they will merge with the extending polypeptide chain and add amino acids to it [1]. It is important to add specific amino acids to the corresponding tRNA, because this means that only when the anti-codon pair (which can form a temporary base pair) is being translated into the next codon for the messenger RNA of the protein Only when certain amino acids are bound to it.

Aminoacyl-tRNA

Right!

Aminoacyl- tRNA (Aminoacyl-tRNA) is a combination of amino acids

Aminoacyl-tRNA (also known as aminoacyl-containing tRNA) is generated in two steps: amino acid activation and amino acid transfer. The first step is adenylation of amino acids, which will form aminoacyl-adenosine monophosphate:

Amino acid + adenosine triphosphate Amino-adenosine monophosphate + pyrophosphate

The amino acid residues are then transferred to the tRNA:

Aminoacyl-adenosine monophosphate + tRNA Aminoacyl-tRNA + adenosine monophosphate

The net response is:

Amino acid + adenosine triphosphate + tRNA Amino-tRNA + adenosine monophosphate + pyrophosphate

This net reaction is thermodynamically advantageous, as pyrolysis of pyrophosphoric acid is thermodynamically advantageous, which drives the reaction to the right. All of these reactions take place inside an aminoacyl-tRNA synthetase that binds to a specific tRNA.

Certain drugs, such as

Berg J, Tymoczko JL, Stryer L. Biochemistry 6th ed. San Francisco: WH Freeman. 2006.ISBN0716787245.

• Aminoacyl tRNA synthetase