What Is an Angiotensin Receptor?

Angiotensin receptors are G protein-coupled receptors with angiotensin as a ligand. [1] It is an important part of the renin-angiotensin system.

Angiotensin receptor

Right!

Angiotensin receptors are based on

The AT ₁ receptor is the most well-studied angiotensin receptor.

mechanism

After AT ₁ receptor is activated by angiotensin II, it is activated by coupled G _{q / 11} and Gi _{/ o}

AT ₂ is abundantly expressed in fetuses and newborns. Its effects include: inhibiting cell growth, fetal tissue development, regulating extracellular matrix, neuronal regeneration, cells

For the AT ₃ and AT ₄ receptors, little is currently known. The AT ₄ receptor can be activated by angiotensin IV, a breakdown product of angiotensin II, and may play an extracellular matrix regulatory role in the central nervous system. ^[1]