What Is Apoptosis-Inducing Factor?
AIF (apoptosis inducing factor) is the first factor cloned in 1999 to induce Caspase-independent apoptosis.
AIF
(Apoptosis inducing factor)
Right!
- Chinese name
- Apoptosis inducing factor
- Foreign name
- apoptosis inducing factor
- Short name
- AIF
- Clone time
- Year 1999
- AIF (apoptosis inducing factor) is the first factor cloned in 1999 to induce Caspase-independent apoptosis.
- Apoptosis Inducing Factor
- It is found in the inner mitochondria. During apoptosis, AIF is transferred from mitochondria to the cytoplasm and then enters the nucleus, causing the DNA in the nucleus to agglutinate and break into 50 kb fragments, which is different from typical apoptosis.
- Taiwan has translated this gene into a "lethal factor" gene. Canadian researchers have discovered this gene, and they believe that if scientists have the ability to regulate this gene, they may be able to prevent the brain cell death of Alzheimer's disease.