What is a Mitochondrial Membrane?
The inner and outer membranes of mitochondria are composed of phospholipid bilayers, in which proteins are embedded, similar to ordinary cell membranes. However, the two membranes have very different characteristics: the outer membrane surrounding the whole organelle contains about 50% by mass of phospholipids, and contains many enzymes, involved in the oxidation of adrenaline, the degradation of tryptophan, and the extension of fatty acids.
Mitochondrial membrane
- Contains many integrations called "channel proteins"
- The mitochondrial inner membrane contains proteins with five types of functions:
- Those executed
- Mitochondrial-Related ER Membrane (MAM)] is an increasingly recognized homeostasis in cell physiology and another key element of its structural role. Once thought to be a technical obstacle in cell separation technology, this often appears that mitochondrial fractions of suspected ER vesicles have been redefined as membrane structures derived from the interface between MAM-mitochondria and ER. The physical coupling between this 2 organelles was previously observed in electron micrographs and was detected with a fluorescence microscope. Such studies estimate that in MAM, which can include up to 20% of the outer mitochondrial membrane, the endoplasmic reticulum and mitochondria are separated by only 10-25 nanometers and held together by protein-bound complexes.
- Isolation and purification of MAM from subcells has been shown to be enriched in participation of phospholipid exchange enzymes, in addition to calcium-related channel signaling. These cues and signal transductions for the prominent role of MAM in the regulation of cellular lipid storage have been confirmed and have a significant effect on mitochondrial-related cellular phenomena, as discussed below. Not only does MAM provide insight into the mechanical foundations, such as the underlying layers of physiological processes such as intrinsic apoptosis and the transmission of calcium signals, but it also facilitates a more accurate picture of mitochondria. Although often seen as static, isolated "Hercules", hijacked cell metabolism through an ancient symbiotic event, the evolution of MAM emphasizes that mitochondria have been incorporated into the overall cellular physiology, with intimate physics and function Degree of coupling to the intimal system.
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