What Is an Oligonucleotide?

Oligonucleotides are a generic term for short-chain nucleotides (including nucleotides in deoxyribonucleic acid DNA or ribonucleic acid RNA) of only 50 or fewer bases. The complementary strand is docked, so it is often used as a probe to determine the structure of DNA or RNA, and is often used in gene chips, electrophoresis, and fluorescence in situ hybridization.

Oligonucleotides

discuss

Oligonucleotides are a generic term for short-chain nucleotides (including nucleotides in deoxyribonucleic acid DNA or ribonucleic acid RNA) with a base size of less than 50 bases. Oligonucleotides can easily The complementary strand is docked, so it is often used as a probe to determine the structure of DNA or RNA, and is often used in gene chips, electrophoresis, and fluorescence in situ hybridization.

Chinese name

Oligonucleotides

Foreign name

oligonucleotide

Nature

Short-chain nucleotides

Used for

Gene chip, electrophoresis, fluorescence in situ hybridization

Response

Chain polymerization

Oligonucleotide-synthesized DNA (deoxyribonucleic acid) can be used for strand polymerization to amplify and determine almost all DNA fragments. In this process, oligonucleotides are used as primers and combined with labeled complementary fragments in DNA to make A replica of DNA.

Regulatory oligonucleotides are used to inhibit RNA fragments, prevent their translation into proteins, and play a role in stopping cancer cell activity.