What Are the Required Hepatitis Immunizations?

Hepatitis B vaccine is a vaccine against infectious diseases caused by the hepatitis B virus, with the liver as the main disease and involving multiple organ damage.

Hepatitis B vaccine

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Hepatitis B vaccine is a vaccine against infectious diseases caused by the hepatitis B virus, with the liver as the main disease and involving multiple organ damage.

Hepatitis B is widely distributed and is endemic to varying degrees throughout the world. China is a high-incidence area of hepatitis B. 60% of the population is infected with hepatitis B virus, and 10% of the population is infected with hepatitis B surface antigen (HBsAg).

Hepatitis B genetic engineering (CHO) vaccine

The vaccine uses genetic engineering technology to recombine the hepatitis B surface antigen gene fragment into Chinese hamster ovary cells (CHO). By proliferating the cell culture, it proliferates and secretes the hepatitis B surface antigen (HBsAg) in the culture solution. Made after alumina, the vaccine has a slight milky white appearance.

Object of vaccination

(1) Those who are susceptible to hepatitis B (surface antigen negative, normal transaminase).

Used to block mother-to-child transmission. Both HBsAg and HBeAg

Hepatitis B Immunoglobulin (HBIG) is an immunoglobulin preparation that is isolated and extracted by high-temperature plasma or serum collected from hepatitis B immunized healthy people by low-temperature ethanol method, combined with low-pH incubation virus inactivation. The liquid preparation is nearly colorless, can be opalescent or light yellow clear liquid, and contains thiomersal preservative.

All pregnant women should be routinely tested for hepatitis B surface antigen (HBsAg) during early prenatal testing. Pregnant women who are positive for hepatitis B surface antigen should check for hepatitis B e antigen (HBeAg) later in pregnancy. If the hepatitis B surface antigen is positive, prepare the hepatitis B vaccine before delivery. At the same time, ask whether the baby can be vaccinated within 24 hours after birth, and where should the second and third shots be given.

Infants with double-positive hepatitis B surface antigen (HBsAg) and hepatitis B e-antigen (HBeAg) mothers should be intramuscularly injected with 1 high-value hepatitis B immunoglobulin within 6-12 hours after birth. One month later, a high-potency hepatitis B immunoglobulin (100 units / ml) was injected. At the age of 2, 3, and 6 months, each received a 20 microgram hepatitis B vaccine.

Newborns born to hepatitis B surface antigen (HBsAg) -positive and hepatitis B e-antigen (HBeAg) -negative mothers should be 10 micrograms, 10 micrograms, 1 and 6 months of age A dose of 10 micrograms was given for hepatitis B vaccine. In areas that do not have the conditions to check for hepatitis B e antigen (HBeAg), newborns of hepatitis B surface antigen (HBsAg) positive mothers should be vaccinated as double positive.

In areas that do not have the conditions to check for hepatitis B surface antigen (HBsAg), all newborns should be vaccinated at 0, 1, and 6 months at a dose of 10 micrograms, 10 micrograms, and 10 micrograms, respectively. ^[2]