What is a Port-Wine Stain?

Red birthmarks, also known as wine stains, flame-like moles, strawberry-like hemangiomas, and strawberry-shaped capillary hemangiomas, often do not show lesions at birth, and the lesions are mostly found within one month after birth, beginning with small red spots After that, it will increase rapidly, and some children stop growing around 1 to 2 years old, but the probability is low. Women are three times as likely as men.

Red birthmark

Red birthmark, also known as wine stain, flame mole, strawberry-like

The cause of the red birthmark is due to the serious lack of zinc, copper, calcium, magnesium and other trace elements in the serum, as well as phenylalanine and tyrosine, which have affected the biochemical process of pigment synthesis, resulting in an abnormal increase in pigment secreted by the pigment cells, and through nerve The plaques that spread gradually cause the epidermis to spread. But the red birthmark with neat edges spreads slowly. The abnormal proliferation of dense blood vessels in the dermis, resulting in dense. Most of them are manifested at birth, and a smaller part is gradually apparent later. Facial torso has a facial torso, and red birthmarks appear localized or widely present. Some red birthmarks will appear soft and bright red like strawberry protruding tissue due to continuous blood vessel proliferation and expansion.

Clinically, photodynamic therapy is used to treat erythema nevus.

Treatment principle

The second generation of a new type of photosensitizer (Hempofen) is injected into the body through the intravenous route. Hempofen forms a peak in blood concentration immediately after intravenous injection, and is quickly absorbed by vascular endothelial cells, while absorbed by epidermal cells Very few, so the distribution of photosensitizers creates a significant concentration difference between vascular endothelial cells and epidermal cells. At this time, light with a specific wavelength that penetrates superficially and can be selectively absorbed by vascular endothelial cells is given, so that Hempofen produces phototoxic substances such as singlet oxygen, and expands the deformed capillaries in the affected area rich in Hempofen. The vascular network is selectively destroyed, while the normal epidermal layer covering the dilated malformed capillary network is not damaged because it does not contain Hempofen, and the normal deep dermal tissue under the dilated malformed capillary network is shallow and difficult to penetrate due to the laser. Protected by reaching effective excitation.

2. Therapeutic effect

Previously developed domestic photosensitizers such as YHpD (photoporphyrin) and HpD (hematoporphyrin derivative) are multi-component mixtures, the components are complex, it is difficult to achieve stable and standardized quality control, and the excretion is slow in the body. Use The post-skin photosensitivity reaction lasts for 1 to 3 months, and some patients even last up to 6 months. This brings great inconvenience to the nursing after treatment and the patient's work and life. ^[1]

Red Birthmark Daily Care

1. The skin where the birthmark is treated needs to fall off by itself. Do not remove it by hand, otherwise the pigmentation is severe and scars are easy to leave.

2. Keep the birthmark treatment area clean to avoid infection and friction.

3. After the scalp peels off, there may be transient pigmentation locally. In order to prevent or reduce this situation, sunscreen and spot removal products can be reasonably applied.

4. After the birthmark treatment, a local cold compress can be done after the treatment site to eliminate or alleviate and accelerate the recovery.