What is the connection between sarcoidosis and vitamin D?
sarcoidosis is a relatively rare autoimmune disorder characterized by body tissue inflammation. It is most often manifested in lungs, eyes, liver, lymph nodes and skin. Inflammation is due to the formation of granulomas of sarcoids and excess vitamin D. The relationship between sarcoidosis and vitamin D is found in granuloma macrophase, which convert vitamin D into 1.2.5-dihdroxy vitamin D, also known as 1.2.5-D. For people without sarcoidosis, this conversion is limited to the kidneys that only create what the body needs.
also called Besnier-Beck or Besnier-Boeck-Shaumann, sarcoidosis results in vitamin D toxicity. Sarcoidosis and toxicity of vitamin D are expanded with a widespread feeling of fatigue, illness and discomfort throughout the body. Other symptoms include joint pain, fever, bloodshed and eye pain.
A number of studies have found that one of the results between sarcoidosis and vitamin D is accelerated by granuloma formav lungs. Sarcoidosis most often begins either in the lungs or in lymphaticCh nodes. It is believed that granulomas contain bacteria that are responsible for excessive vitamin D. This causes increased inflammation that leads to an increase in discomfort.
The cause of this disease is unknown, although the connection between sarcoidosis and vitamin D has been well introduced. This condition is known that most patients show an active phase and inactive phase. Some patients experience much milder symptoms than others, and in some cases, this disease seems to be resolved in itself.
During the active phase, symptoms occur due to granuloma formation and subsequent production of excess vitamin D. In some cases, scars tissue develops on the real organs, which deepens the problem. In an inactive phase, inflammation decreases, leading to several few or no symptoms.
While sarcoidosis is most common in lungs, eyes, skin, lymph nodes and liverH, it is also known to affect the heart and the nervous system, including the brain. In very rare cases, sarcoidosis can also affect kidneys, reproductive organs and thyroid gland. The worsening of the disease occurs slowly, in some cases over the years. The cause is unknown and while treatment can help alleviate symptoms, there is no known drug.
patients with sarcoidosis and vitamin D toxicity should reduce the exposure to sunlight, creating vitamin D in the body. The consumption of foods with a high content of vitamin D, such as dairy products, should also avoid. Patients taking vitamins should be careful to prevent patients containing vitamin D.