What Is Carcinoma In Situ?
Carcinoma in situ is also called Bowen's disease, or intraepithelial carcinoma. It is more common in the elderly and occurs at the junction of the cornea and conjunctiva. There is a clear boundary between the tumor and adjacent normal tissue. It develops slowly and can be confined to the epithelium for several years. Pathological examination shows an irregular epidermal hyperplasia, which is a true intraepithelial carcinoma. Epithelial cell polarity disorder can be seen in the section. Normal epithelial cells have been replaced by many heterogeneous or multinuclear singular cells. Common keratinized and incompletely divided divisions are common. The epithelial basement membrane is intact and the prognosis is generally good.
Carcinoma in situ
- Carcinoma in situ is also called Bowen's disease, or intraepithelial carcinoma. It is more common in the elderly and occurs at the junction of the cornea and conjunctiva. There is a clear boundary between the tumor and adjacent normal tissue. Development is slow and can be confined to the epithelium for several years,
- Tumor located
- Diagnose based on
- 1. A mass at the junction of the conjunctiva, which develops slowly.
- 2. The result of pathological examination after mass resection is the most reliable basis for diagnosis of this disease.
Cancer in situ treatment principles
- 1. Completely remove the tumor.
- 2. Lamellar corneal transplantation.
Cancer in situ medication principles
- Surgical treatment is mainly based on topical antibiotics and corticosteroids, supplemented with nutrition and supportive treatment. Cyclosporin A can be applied locally or systemically if necessary.