What is Microarray DNA?

Microarray DNA technology is used in genetic and medical research to allow scientists to study several thousand genes at the same time as well as the relationship between them. In the past, scientists have been able to analyze only a few genes at a time. When introducing Microorrant DNA technology, thousands of genes can be monitored simultaneously. Some of the health conditions that scientists use this technology to research gene activity include heart disease, cancer and obesity. It also allows scientists to classify cancer based on where they come and the pattern of gene activity in the tumor cell. The DNA is placed on a glass in a specific sequence and in the formula of regularly distributed horizontal and vertical lines with a robotic machine. Specific sequences and DNA spacing allow scientists to know the sequence used by the gene (gene).

Before the scientist is able to measure the activity of the gene on the image, the pattern should be collectedto the tissue from the patient, usually blood. The tissue sample is placed in a solution and allows the collection of MRNA, a product from an expressed gene that transports information from the nucleus to other parts of the cell to produce proteins. MRNA is a complement to the spring of the bottom from which it was copied.

As soon as the mRNA is collected, the scientist binds the fluorescent dye to the MRNA and will be placed on the glass of a robotic machine. MRNA, which is complementary DNA, is bound to its complement. Because the DNA sequence, which was located in the image, is known, the MRNA, which binds to the DNA, indicates a specific DNA sequence that is expressed in the cell.

If you want to view genes, Will Measure the fluorescent area of ​​the microchip of the DNA microchip. The brightness of the fluorescent dye shows the activity of the gene and the absence of a fluorescent dye suggests that the gene is not active. The brighter is the fluorescent dye, the more active the gene. The lighter the fluorescent dye, the less the gene.

Knowledge of a gene activity can help determine whether the gene,that is excessively expressed can cause specific diseases. In the clinical environment, if excessive gene expression has already been determined to cause specific diseases, the tissue sample may be taken from the patient and the scientist can use DNA technology to measure the expression of targeted gene to help determine whether a particular gene can cause the patient. Microarray DNA is a powerful way to determine which genes are involved in causing specific diseases.

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